Recombinant Human BHMT, GST-tagged

• Cat.No.: BHMT-10223H
• Product Overview: Recombinant Human BHMT protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: This gene encodes a cytosolic enzyme that catalyzes the conversion of betaine and homocysteine to dimethylglycine and methionine, respectively. Defects in this gene could lead to hyperhomocyst(e)inemia, but such a defect has not yet been observed.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-406a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: BHMT betaine--homocysteine S-methyltransferase [ Homo sapiens ]
• Official Symbol: BHMT
• Synonyms: BHMT; betaine--homocysteine S-methyltransferase; betaine--homocysteine S-methyltransferase 1; betaine homocysteine methyltransferase; BHMT1
• Gene ID: 635
• mRNA Refseq: NM_001713
• Protein Refseq: NP_001704
• MIM: 602888
• UniProt ID: Q93088
• Chromosome Location: 5q13.1-q15
• Pathway: Cysteine and methionine metabolism, organism-specific biosystem; Cysteine and methionine metabolism, conserved biosystem; Glycine, serine and threonine metabolism, organism-specific biosystem; Glycine, serine and threonine metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem
• Function: betaine-homocysteine S-methyltransferase activity; betaine-homocysteine S-methyltransferase activity; homocysteine S-methyltransferase activity; metal ion binding; methyltransferase activity; protein complex binding; transferase activity; zinc ion binding