Recombinant Human CA2, GST-tagged
Cat.No. : | CA2-10619H |
Product Overview : | Recombinant Human CA2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | CA2 is one of several (at least 7) isozymes of carbonic anhydrase. Carbonic anhydrase catalyzes reversible hydration of carbon dioxide. Defects in this enzyme are associated with osteopetrosis and renal tubular acidosis. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-260a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | CA2 carbonic anhydrase II [ Homo sapiens ] |
Official Symbol : | CA2 |
Synonyms : | CA2; carbonic anhydrase II; carbonic anhydrase 2; CA II; CAII; Car2; CAC; carbonic anhydrase B; carbonic anhydrase C; carbonic dehydratase; carbonate dehydratase II; CA-II; |
Gene ID : | 760 |
mRNA Refseq : | NM_000067 |
Protein Refseq : | NP_000058 |
MIM : | 611492 |
UniProt ID : | P00918 |
Chromosome Location : | 8q22 |
Pathway : | Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Collecting duct acid secretion, organism-specific biosystem; Collecting duct acid secretion, conserved biosystem; Gastric acid secretion, organism-specific biosystem; Gastric acid secretion, conserved biosystem; Pancreatic secretion, organism-specific biosystem; |
Function : | carbonate dehydratase activity; lyase activity; metal ion binding; zinc ion binding; |
Products Types
◆ Recombinant Protein | ||
CA2-716R | Recombinant Rat CA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CA2-1158M | Recombinant Mouse CA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CA2-479H | Recombinant Human CA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CA2-114H | Recombinant Human CA2 Protein, His-tagged | +Inquiry |
CA2-0238H | Recombinant Human CA2 Protein, GST-Tagged | +Inquiry |
◆ Native Protein | ||
CA2-34R | Native Rabbit Carbonic Anhydrase II (CA2) Protein | +Inquiry |
CA2-35R | Native Rhesus monkey Carbonic Anhydrase II (CA2) Protein | +Inquiry |
CA2-29D | Native Dog Carbonic Anhydrase II (CA2) Protein | +Inquiry |
◆ Lysates | ||
CA2-7915HCL | Recombinant Human CA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCA2 deficiency is a rare autosomal recessive disorder with metabolic acidosis and osteopetrosis.
Acetazolamide is a known inhibitor, used clinically for glaucoma and altitude sickness.
Some mutations can lead to CA2 deficiency, affecting acid-base balance and leading to metabolic acidosis.
CA2 is one of the most efficient and fastest enzymes, displaying higher activity than many other isoforms.
CA2 accelerates the reversible conversion of CO2 and water to bicarbonate and protons, aiding in pH regulation.
CA2 plays a crucial role in CO2 transport and acid-base balance in various tissues.
CA2 is ubiquitously expressed but is particularly abundant in red blood cells and certain epithelial tissues.
Customer Reviews (3)
Write a reviewEfficient sample processing, a time-saving boon for researchers.
Professional expertise, elevates our protein research projects.
Invaluable assistance for intricate protein experiments.
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