Recombinant Human CADM2, His-tagged
Cat.No. : | CADM2-10652H |
Product Overview : | Recombinant Human CADM2 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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- Gene Information
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Description : | This gene encodes a member of the synaptic cell adhesion molecule 1 (SynCAM) family which belongs to the immunoglobulin (Ig) superfamily. The encoded protein has three Ig-like domains and a cytosolic protein 4.1 binding site near the C-terminus. Proteins belonging to the protein 4.1 family crosslink spectrin and interact with other cytoskeletal proteins. Multiple transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 28-404a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | CADM2 cell adhesion molecule 2 [ Homo sapiens ] |
Official Symbol : | CADM2 |
Synonyms : | CADM2; cell adhesion molecule 2; IGSF4D, immunoglobulin superfamily, member 4D; Necl 3; NECL3; nectin like 3; SynCAM2; nectin-like 3; nectin-like protein 3; immunoglobulin superfamily member 4D; immunoglobulin superfamily, member 4D; IGSF4D; Necl-3; synCAM2; MGC104534; MGC138341; MGC138343; |
Gene ID : | 253559 |
mRNA Refseq : | NM_001167674 |
Protein Refseq : | NP_001161146 |
MIM : | 609938 |
UniProt ID : | Q8N3J6 |
Chromosome Location : | 3p12.2 |
Pathway : | Adherens junctions interactions, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
CADM2-354H | Recombinant Human CADM2 Protein, His-tagged | +Inquiry |
CADM2-744R | Recombinant Rat CADM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CADM2-1183M | Recombinant Mouse CADM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CADM2-2583H | Recombinant Human CADM2 Protein, His (Fc)-Avi-tagged | +Inquiry |
CADM2-714H | Recombinant Human CADM2 Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionCADM2's role in immune cell adhesion and recognition is relevant to vaccine development and immunotherapy strategies, as it influences immune cell interactions and responses.
CADM2 expression varies during development and contributes to tissue development and cellular differentiation, particularly in the nervous system
CADM2 is essential for neural cell adhesion and synaptic plasticity, contributing to the formation and maintenance of neural connections. Dysregulation of CADM2 has been linked to neurological disorders like schizophrenia and autism spectrum disorders.
CADM2 plays a role in immune cell interactions and modulates immune responses. Its involvement in autoimmune diseases and cancer immunology is an area of ongoing research.
Post-translational modifications, such as phosphorylation and glycosylation, modulate CADM2's interactions and functions, affecting cellular adhesion and signaling pathways.
Customer Reviews (3)
Write a reviewThis is hands down the best product I've ever tried.
It's made a significant difference in my workouts and recovery time.
I've been using the product for a few months now, and it has exceeded my expectations.
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