Recombinant Human CDC6, GST-tagged

• Cat.No.: CDC6-11018H
• Product Overview: Recombinant Human CDC6 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: CD300LB is a nonclassical activating receptor of the immunoglobulin (Ig) superfamily expressed on myeloid cells (Martinez-Barriocanal and Sayos, 2006 [PubMed 16920917]).
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: C-term-343a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: CDC6 cell division cycle 6 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: CDC6
• Synonyms: CDC6; cell division cycle 6 homolog (S. cerevisiae); CDC6 (cell division cycle 6, S. cerevisiae) homolog , CDC6 cell division cycle 6 homolog (S. cerevisiae) , CDC18L; cell division control protein 6 homolog; p62(cdc6); CDC6-related protein; cdc18-related protein; CDC6 cell division cycle 6 homolog; CDC18L; HsCDC6; HsCDC18
• Gene ID: 990
• mRNA Refseq: NM_001254
• Protein Refseq: NP_001245
• MIM: 602627
• UniProt ID: Q99741
• Chromosome Location: 17q21.3
• Pathway: Activation of ATR in response to replication stress, organism-specific biosystem; Activation of the pre-replicative complex, organism-specific biosystem; Assembly of the pre-replicative complex, organism-specific biosystem; Association of licensing factors with the pre-replicative complex, organism-specific biosystem; CDC6 association with the ORC:origin complex, organism-specific biosystem; CDK-mediated phosphorylation and removal of Cdc6, organism-specific biosystem; CDT1 association with the CDC6:ORC:origin complex, organism-specific biosystem
• Function: ATP binding; chromatin binding; kinase binding; nucleoside-triphosphatase activity; nucleotide binding; protein binding