Recombinant Human COL2A1, His-tagged
Cat.No. : | COL2A1-11432H |
Product Overview : | Recombinant Human COL2A1 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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- Gene Information
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Description : | This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | C-288a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | COL2A1 collagen, type II, alpha 1 [ Homo sapiens ] |
Official Symbol : | COL2A1 |
Synonyms : | COL2A1; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital) , SEDC; collagen alpha-1(II) chain; chondrocalcin; cartilage collagen; alpha-1 type II collagen; collagen II, alpha-1 polypeptide; AOM; ANFH; SEDC; COL11A3; MGC131516; |
Gene ID : | 1280 |
mRNA Refseq : | NM_001844 |
Protein Refseq : | NP_001835 |
UniProt ID : | P02458 |
Chromosome Location : | 12q12-q13.2 |
Pathway : | Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Axon guidance, organism-specific biosystem; Developmental Biology, organism-specific biosystem; ECM-receptor interaction, organism-specific biosystem; ECM-receptor interaction, conserved biosystem; Endochondral Ossification, organism-specific biosystem; |
Function : | extracellular matrix structural constituent conferring tensile strength; identical protein binding; platelet-derived growth factor binding; |
Products Types
◆ Recombinant Protein | ||
COL2A1-1178R | Recombinant Rat COL2A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
COL2A1-1649H | Recombinant Human COL2A1 Protein, GST-tagged | +Inquiry |
COL2A1-2155H | Recombinant Human COL2A1 Protein, His-tagged | +Inquiry |
COL2A1-2712H | Recombinant Human COL2A1 Protein, His (Fc)-Avi-tagged | +Inquiry |
COL2A1-3929H | Recombinant Human COL2A1 protein(Asp1242-Leu1487), His-tagged | +Inquiry |
◆ Native Protein | ||
COL2A1-15C | Native Chicken COL2A1 Protein | +Inquiry |
COL2A1-1648H | Native Human COL2A1 Protein | +Inquiry |
COL2A1-13B | Native Bovine COL2A1 Protein | +Inquiry |
◆ Lysates | ||
COL2A1-2063HCL | Recombinant Human COL2A1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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