Recombinant Human EDNRB, His-tagged
Cat.No. : | EDNRB-12286H |
Product Overview : | Recombinant Human EDNRB protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: ET1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 27-99a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | EDNRB endothelin receptor type B [ Homo sapiens ] |
Official Symbol : | EDNRB |
Synonyms : | EDNRB; endothelin receptor type B; HSCR, HSCR2; endothelin B receptor; ETB; endothelin receptor non-selective type; ET-B; ETBR; ETRB; HSCR; WS4A; ABCDS; ET-BR; HSCR2; |
Gene ID : | 1910 |
mRNA Refseq : | NM_000115 |
Protein Refseq : | NP_000106 |
MIM : | 131244 |
UniProt ID : | P24530 |
Chromosome Location : | 13q22 |
Pathway : | Arf6 trafficking events, organism-specific biosystem; Calcium signaling pathway, organism-specific biosystem; Calcium signaling pathway, conserved biosystem; Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; Endothelins, organism-specific biosystem; G alpha (q) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; |
Function : | G-protein coupled receptor activity; endothelin receptor activity; endothelin receptor activity; endothelin receptor activity; peptide hormone binding; receptor activity; signal transducer activity; |
Products Types
◆ Recombinant Protein | ||
EDNRB-1209H | Recombinant Human EDNRB Protein, MYC/DDK-tagged | +Inquiry |
EDNRB-1669R | Recombinant Rat EDNRB Protein, His (Fc)-Avi-tagged | +Inquiry |
Ednrb-2730M | Recombinant Mouse Ednrb Protein, Myc/DDK-tagged | +Inquiry |
EDNRB-687H | Recombinant Human EDNRB protein(Met1-Lys101), His-tagged | +Inquiry |
EDNRB-2642M | Recombinant Mouse EDNRB Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
EDNRB-001HCL | Recombinant Human EDNRB cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-1231 | EDNRB Total GPCR Internalization Assay Kit | +Inquiry |
Kit-1230 | EDNRB CHO-K1 β-Arrestin GPCR Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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