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Recombinant Human EGR2, GST-tagged

Cat.No. : EGR2-12329H
Product Overview : Recombinant Human EGR2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Description : The protein encoded by this gene is a transcription factor with three tandem C2H2-type zinc fingers. Defects in this gene are associated with Charcot-Marie-Tooth disease type 1D (CMT1D), Charcot-Marie-Tooth disease type 4E (CMT4E), and with Dejerine-Sottas syndrome (DSS). Multiple transcript variants encoding two different isoforms have been found for this gene.
Source : E.coli
Species : Human
Tag : GST
Protein length : 149-499a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : EGR2 early growth response 2 [ Homo sapiens ]
Official Symbol : EGR2
Synonyms : EGR2; early growth response 2; early growth response 2 (Krox 20 homolog, Drosophila) , KROX20; E3 SUMO-protein ligase EGR2; Krox 20 homolog; Drosophila; zinc finger protein Krox-20; early growth response protein 2; KROX-20, Drosophila, homolog (early growth response-2); AT591; CMT1D; CMT4E; KROX20; FLJ14547; DKFZp686J1957;
Gene ID : 1959
mRNA Refseq : NM_000399
Protein Refseq : NP_000390
MIM : 129010
UniProt ID : P11161
Chromosome Location : 10q21.1
Pathway : Adipogenesis, organism-specific biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; Developmental Biology, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; HTLV-I infection, conserved biosystem; IL4-mediated signaling events, organism-specific biosystem; Transcriptional Regulation of White Adipocyte Differentiation, organism-specific biosystem;
Function : DNA binding; RNA polymerase II activating transcription factor binding; chromatin binding; ligase activity; metal ion binding; protein binding; sequence-specific DNA binding transcription factor activity; transcription regulatory region DNA binding; ubiqu

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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