Recombinant Human F9, His-tagged
Cat.No. : | F9-12627H |
Product Overview : | Recombinant Human F9 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 129-395a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | F9 coagulation factor IX [ Homo sapiens ] |
Official Symbol : | F9 |
Synonyms : | F9; coagulation factor IX; Christmas disease; Factor IX; FIX; hemophilia B; plasma thromboplastic component; F9 p22; FIX F9; factor 9; factor IX F9; serine protease; Christmas factor; plasma thromboplastin component; P19; PTC; HEMB; THPH8; MGC129641; MGC129642; |
Gene ID : | 2158 |
mRNA Refseq : | NM_000133 |
Protein Refseq : | NP_000124 |
MIM : | 300746 |
UniProt ID : | P00740 |
Chromosome Location : | Xq26.3-q27.1 |
Pathway : | Blood Clotting Cascade, organism-specific biosystem; Complement and Coagulation Cascades, organism-specific biosystem; Complement and coagulation cascades, organism-specific biosystem; Complement and coagulation cascades, conserved biosystem; Extrinsic Pathway, organism-specific biosystem; Formation of Fibrin Clot (Clotting Cascade), organism-specific biosystem; Gamma-carboxylation of protein precursors, organism-specific biosystem; |
Function : | calcium ion binding; peptidase activity; serine-type endopeptidase activity; |
Products Types
◆ Recombinant Protein | ||
F9-1358R | Recombinant Rhesus Macaque F9 Protein, His (Fc)-Avi-tagged | +Inquiry |
F9-914R | Recombinant Rabbit F9 Protein, His-tagged | +Inquiry |
F9-2502H | Recombinant Human F9 protein(51-120 aa), C-His-tagged | +Inquiry |
F9-3626H | Recombinant Human F9 Protein, GST-tagged | +Inquiry |
F9-915R | Recombinant Rabbit F9 Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
F9-5405M | Native Mouse Coagulation Factor IX | +Inquiry |
F9-26523H | Active Native Human F9 Protein | +Inquiry |
F9-301R | Native Rat Factor IXa | +Inquiry |
◆ Lysates | ||
F9-1768MCL | Recombinant Mouse F9 cell lysate | +Inquiry |
F9-1849HCL | Recombinant Human F9 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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