Recombinant Human FBXO32, GST-tagged
Cat.No. : | FBXO32-12796H |
Product Overview : | Recombinant Human FBXO32 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Description : | This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and contains an F-box domain. This protein is highly expressed during muscle atrophy, whereas mice deficient in this gene were found to be resistant to atrophy. This protein is thus a potential drug target for the treatment of muscle atrophy. Alternative splicing results in multiple transcript variants encoding different isoforms. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | C-term-217a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | FBXO32 F-box protein 32 [ Homo sapiens ] |
Official Symbol : | FBXO32 |
Synonyms : | FBXO32; F-box protein 32; F box only protein 32; F-box only protein 32; ATROGIN1; Fbx32; MAFbx; atrogin 1; atrogin-1; muscle atrophy F-box protein; FLJ32424; MGC33610; |
Gene ID : | 114907 |
mRNA Refseq : | NM_001242463 |
Protein Refseq : | NP_001229392 |
MIM : | 606604 |
UniProt ID : | Q969P5 |
Chromosome Location : | 8q24.13 |
Pathway : | FoxO family signaling, organism-specific biosystem; Monoamine Transport, organism-specific biosystem; |
Products Types
◆ Recombinant Protein | ||
FBXO32-237H | Recombinant Human FBXO32 Protein, His-tagged | +Inquiry |
FBXO32-1487R | Recombinant Rhesus Macaque FBXO32 Protein, His (Fc)-Avi-tagged | +Inquiry |
FBXO32-3936H | Recombinant Human FBXO32 Protein, GST-tagged | +Inquiry |
FBXO32-1952R | Recombinant Rat FBXO32 Protein, His (Fc)-Avi-tagged | +Inquiry |
FBXO32-3160M | Recombinant Mouse FBXO32 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FBXO32-6297HCL | Recombinant Human FBXO32 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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