Recombinant Human FGF20, GST-tagged

• Cat.No.: FGF20-12869H
• Product Overview: Recombinant Human FGF20 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a member of the fibroblast growth factor family. The fibroblast growth factors possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This gene product is a secreted neurotrophic factor but lacks a typical signal peptide. It is expressed in normal brain, particularly the cerebellum, and may regulate central nervous system development and function. Homodimerization of this protein was shown to regulate its receptor binding activity and concentration gradient in the extracellular matrix. Genetic variations of this gene have been associated with Parkinson disease susceptibility.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 1-64a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FGF20 fibroblast growth factor 20 [ Homo sapiens ]
• Official Symbol: FGF20
• Synonyms: FGF20; fibroblast growth factor 20; FGF-20
• Gene ID: 26281
• mRNA Refseq: NM_019851
• Protein Refseq: NP_062825
• MIM: 605558
• UniProt ID: Q9NP95
• Chromosome Location: 8p22
• Pathway: Downstream signaling of activated FGFR, organism-specific biosystem; FGFR ligand binding and activation, organism-specific biosystem; FGFR1 ligand binding and activation, organism-specific biosystem; FGFR1c ligand binding and activation, organism-specific biosystem; FGFR2 ligand binding and activation, organism-specific biosystem; FGFR2c ligand binding and activation, organism-specific biosystem; FGFR3 ligand binding and activation, organism-specific biosystem
• Function: fibroblast growth factor receptor binding; growth factor activity; protein tyrosine kinase activity