Recombinant Human FKBP14, GST-tagged

• Cat.No.: FKBP14-12908H
• Product Overview: Recombinant Human FKBP14 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: The protein encoded by this gene is a member of the FK506-binding protein family of peptidyl-prolyl cis-trans isomerases. The encoded protein is found in the lumen of the endoplasmic reticulum, where it is thought to accelerate protein folding. Defects in this gene are a cause of a type of Ehlers-Danlos syndrome (EDS). Both a protein-coding variant and noncoding variants are transcribed from this gene.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 21-211a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: FKBP14 FK506 binding protein 14, 22 kDa [ Homo sapiens ]
• Official Symbol: FKBP14
• Synonyms: FKBP14; FK506 binding protein 14, 22 kDa; FK506 binding protein 14 (22 kDa); peptidyl-prolyl cis-trans isomerase FKBP14; FKBP22; FLJ20731; FKBP-22; rotamase; 22 kDa FKBP; PPIase FKBP14; FK506-binding protein 14; 22 kDa FK506-binding protein; EDSKMH
• Gene ID: 55033
• mRNA Refseq: NM_017946
• Protein Refseq: NP_060416
• MIM: 614505
• UniProt ID: Q9NWM8
• Chromosome Location: 7p15
• Pathway: Activation of Chaperone Genes by XBP1(S), organism-specific biosystem; Activation of Chaperones by IRE1alpha, organism-specific biosystem; Diabetes pathways, organism-specific biosystem; Disease, organism-specific biosystem; Unfolded Protein Response, organism-specific biosystem
• Function: FK506 binding; calcium ion binding; isomerase activity; peptidyl-prolyl cis-trans isomerase activity