Recombinant Human FSHR, His-tagged
Cat.No. : | FSHR-13016H |
Product Overview : | Recombinant Human FSHR protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | The protein encoded by this gene belongs to family 1 of G-protein coupled receptors. It is the receptor for follicle stimulating hormone and functions in gonad development. Mutations in this gene cause ovarian dysgenesis type 1, and also ovarian hyperstimulation syndrome. Alternative splicing results in multiple transcript variants. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 18-352a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | FSHR follicle stimulating hormone receptor [ Homo sapiens ] |
Official Symbol : | FSHR |
Synonyms : | FSHR; follicle stimulating hormone receptor; ODG1; follicle-stimulating hormone receptor; FSHRO; LGR1; FSH receptor; follitropin receptor; MGC141667; MGC141668; |
Gene ID : | 2492 |
mRNA Refseq : | NM_000145 |
Protein Refseq : | NP_000136 |
MIM : | 136435 |
UniProt ID : | P23945 |
Chromosome Location : | 2p21-p16 |
Pathway : | Class A/1 (Rhodopsin-like receptors), organism-specific biosystem; G alpha (s) signalling events, organism-specific biosystem; GPCR downstream signaling, organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; GPCRs, Class A Rhodopsin-like, organism-specific biosystem; GPCRs, Other, organism-specific biosystem; Hormone ligand-binding receptors, organism-specific biosystem; |
Function : | follicle-stimulating hormone receptor activity; peptide hormone binding; protein binding; receptor activity; signal transducer activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionFSHR regulates bone density, with implications for osteoporosis risk, particularly post-menopause.
Changes in FSHR signaling can influence the efficacy and outcomes of hormone replacement therapies.
FSHR is key in stimulating ovarian follicle growth and triggering ovulation in women.
FSHR plays a significant role in male fertility, essential for the process of spermatogenesis.
Mutations in FSHR can lead to fertility issues and reproductive disorders in both sexes.
FSHR affects hormonal balance and menstrual cycle regulation in females.
FSHR is involved in PCOS pathogenesis, potentially affecting ovarian function and hormone levels.
Customer Reviews (3)
Write a reviewExceptional protein expression optimization support, highly appreciated assistance.
Accurate protein structural analysis, indispensable for our investigations.
Timely antibody validation, an invaluable asset for our laboratory.
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