Recombinant Human GBA3, His-tagged

• Cat.No.: GBA3-13175H
• Product Overview: Recombinant Human GBA3 protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Description: Glutathione S-transferases (GSTs) are a family of enzymes that play an important role in detoxification by catalyzing the conjugation of many hydrophobic and electrophilic compounds with reduced glutathione. Based on their biochemical, immunologic, and structural properties, the soluble GSTs are categorized into 4 main classes: alpha, mu, pi, and theta. This GST family member is a polymorphic gene encoding active, functionally different GSTP1 variant proteins that are thought to function in xenobiotic metabolism and play a role in susceptibility to cancer, and other diseases.
• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 1-162a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: GBA3 glucosidase, beta, acid 3 (cytosolic) [ Homo sapiens ]
• Official Symbol: GBA3
• Synonyms: GBA3; glucosidase, beta, acid 3 (cytosolic); cytosolic beta-glucosidase; GLUC; klotho related protein; KLrP; klotho-related protein; cytosolic beta-glucosidase-like protein 1; CBGL1; MGC104276; MGC126878
• Gene ID: 57733
• mRNA Refseq: NM_001128432
• Protein Refseq: NP_001121904
• MIM: 606619
• UniProt ID: Q9H227
• Chromosome Location: 4p15.31
• Pathway: Cyanoamino acid metabolism, organism-specific biosystem; Cyanoamino acid metabolism, conserved biosystem; Glycosphingolipid metabolism, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of lipids and lipoproteins, organism-specific biosystem; Sphingolipid metabolism, organism-specific biosystem
• Function: beta-galactosidase activity; beta-glucosidase activity; cation binding; glycosylceramidase activity