Recombinant Human GBP1, GST-tagged

• Cat.No.: GBP1-13180H
• Product Overview: Recombinant Human GBP1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.

Specification

• Description: Glutathione S-transferase (GSTs) theta 2 (GSTT2) is a member of a superfamily of proteins that catalyze the conjugation of reduced glutathione to a variety of electrophilic and hydrophobic compounds. Human GSTs can be divided into five main classes: Alpha, Mu, Pi, Theta, and Zeta. The theta class members GSTT1 and GSTT2 share 55% amino acid sequence identity and both are thought to have an important role in human carcinogenesis. The theta genes have a similar structure, being composed of five exons with identical exon/intron boundaries.
• Source: E.coli
• Species: Human
• Tag: GST
• Protein length: 242-592a.a.
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.

Gene Information

• Gene Name: GBP1 guanylate binding protein 1, interferon-inducible [ Homo sapiens ]
• Official Symbol: GBP1
• Synonyms: GBP1; guanylate binding protein 1, interferon-inducible; guanylate binding protein 1, interferon inducible, 67kDa; interferon-induced guanylate-binding protein 1; GBP-1; huGBP-1; GTP-binding protein 1; guanine nucleotide-binding protein 1; guanylate binding protein 1, interferon-inducible, 67kDa
• Gene ID: 2633
• mRNA Refseq: NM_002053
• Protein Refseq: NP_002044
• MIM: 600411
• UniProt ID: P32455
• Chromosome Location: 1p22.2
• Pathway: Cytokine Signaling in Immune system, organism-specific biosystem; Immune System, organism-specific biosystem; Interferon Signaling, organism-specific biosystem; Interferon gamma signaling, organism-specific biosystem; Type II interferon signaling (IFNG), organism-specific biosystem
• Function: GTP binding; GTPase activity; nucleotide binding