Recombinant Human GDF5, GST-tagged
Cat.No. : | GDF5-13211H |
Product Overview : | Recombinant Human GDF5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 143-501a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | GDF5 growth differentiation factor 5 [ Homo sapiens ] |
Official Symbol : | GDF5 |
Synonyms : | GDF5; growth differentiation factor 5; growth/differentiation factor 5; BMP14; cartilage derived morphogenetic protein 1; CDMP1; GDF-5; CDMP-1; radotermin; cartilage-derived morphogenetic protein-1; OS5; LAP4; SYNS2; |
Gene ID : | 8200 |
mRNA Refseq : | NM_000557 |
Protein Refseq : | NP_000548 |
MIM : | 601146 |
UniProt ID : | P43026 |
Chromosome Location : | 20q11.2 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem; |
Function : | cytokine activity; growth factor activity; |
Products Types
◆ Recombinant Protein | ||
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Gdf5-065M | Active Recombinant Mouse Gdf5 Protein | +Inquiry |
Gdf5-276M | Recombinant Mouse Gdf5 Protein, His-tagged | +Inquiry |
GDF5-3521M | Recombinant Mouse GDF5 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
GDF5-5968HCL | Recombinant Human GDF5 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionGDF5 has been found to stimulate the proliferation and differentiation of chondrocytes, the cells responsible for cartilage formation and maintenance.
Preclinical studies have demonstrated GDF5's ability to promote bone and cartilage regeneration in animal models, providing a foundation for further clinical exploration.
GDF5's specificity for bone and cartilage development distinguishes it from other growth factors, making it a targeted option for orthopedic interventions.
Some studies suggest that combining GDF5 with other growth factors or therapeutic approaches may result in synergistic effects, improving overall outcomes.
While its primary focus is on musculoskeletal conditions, GDF5's role in cellular differentiation opens avenues for exploring its applications in broader regenerative medicine contexts.
Customer Reviews (3)
Write a reviewTheir dedicated team of experts is prompt, knowledgeable, and readily available to tackle any hurdles or concerns I may encounter.
Used in protein electron microscopy structure analysis.Great.
By harnessing the power of the GDF5 protein, I can harness its outstanding quality and tap into its potential to obtain dependable and meaningful findings.
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