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Recombinant Human GDF5, GST-tagged

Cat.No. : GDF5-13211H
Product Overview : Recombinant Human GDF5 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : 143-501a.a.
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : GDF5 growth differentiation factor 5 [ Homo sapiens ]
Official Symbol : GDF5
Synonyms : GDF5; growth differentiation factor 5; growth/differentiation factor 5; BMP14; cartilage derived morphogenetic protein 1; CDMP1; GDF-5; CDMP-1; radotermin; cartilage-derived morphogenetic protein-1; OS5; LAP4; SYNS2;
Gene ID : 8200
mRNA Refseq : NM_000557
Protein Refseq : NP_000548
MIM : 601146
UniProt ID : P43026
Chromosome Location : 20q11.2
Pathway : Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; TGF-beta signaling pathway, organism-specific biosystem; TGF-beta signaling pathway, conserved biosystem;
Function : cytokine activity; growth factor activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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How does GDF5 contribute to cartilage repair? 10/10/2022

GDF5 has been found to stimulate the proliferation and differentiation of chondrocytes, the cells responsible for cartilage formation and maintenance.

What preclinical evidence supports the use of GDF5 in orthopedics? 01/16/2021

Preclinical studies have demonstrated GDF5's ability to promote bone and cartilage regeneration in animal models, providing a foundation for further clinical exploration.

How does GDF5 differ from other growth factors in terms of clinical applications? 10/01/2017

GDF5's specificity for bone and cartilage development distinguishes it from other growth factors, making it a targeted option for orthopedic interventions.

Can GDF5 be used in combination with other therapies for enhanced effects? 09/06/2017

Some studies suggest that combining GDF5 with other growth factors or therapeutic approaches may result in synergistic effects, improving overall outcomes.

Is GDF5 only relevant for bone and cartilage conditions, or are there other potential applications? 08/18/2017

While its primary focus is on musculoskeletal conditions, GDF5's role in cellular differentiation opens avenues for exploring its applications in broader regenerative medicine contexts.

Customer Reviews (3)

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06/26/2022

    Their dedicated team of experts is prompt, knowledgeable, and readily available to tackle any hurdles or concerns I may encounter.

    03/20/2020

      Used in protein electron microscopy structure analysis.Great.

      08/31/2019

        By harnessing the power of the GDF5 protein, I can harness its outstanding quality and tap into its potential to obtain dependable and meaningful findings.

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