Recombinant Human GNE, His-tagged
Cat.No. : | GNE-13359H |
Product Overview : | Recombinant Human GNE protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose. |
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Description : | This gene encodes a member of the glutaredoxin family. Glutaredoxins are oxidoreductase enzymes that reduce a variety of substrates using glutathione as a cofactor. The encoded protein binds to and modulates the function of protein kinase C theta. The encoded protein may also inhibit apoptosis and play a role in cellular growth, and the expression of this gene may be a marker for cancer. Pseudogenes of this gene are located on the short arm of chromosomes 6 and 9. Alternatively spliced transcript variants have been observed for this gene. |
Source : | E.coli |
Species : | Human |
Tag : | His |
Protein length : | 376-722a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol. |
Gene Name : | GNE glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase [ Homo sapiens ] |
Official Symbol : | GNE |
Synonyms : | GNE; glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase; IBM2, UDP N acetylglucosamine 2 epimerase/N acetylmannosamine kinase; bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; Uae1; N-acylmannosamine kinase; UDP-GlcNAc-2-epimerase/ManAc kinase; UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase; UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kinase; NM; DMRV; IBM2; GLCNE; |
Gene ID : | 10020 |
mRNA Refseq : | NM_001128227 |
Protein Refseq : | NP_001121699 |
MIM : | 603824 |
UniProt ID : | Q9Y223 |
Chromosome Location : | 9p13.1 |
Pathway : | Amino sugar and nucleotide sugar metabolism, organism-specific biosystem; Amino sugar and nucleotide sugar metabolism, conserved biosystem; CMP-N-acetylneuraminate biosynthesis I (eukaryotes), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
Function : | ATP binding; N-acylmannosamine kinase activity; UDP-N-acetylglucosamine 2-epimerase activity; isomerase activity; kinase activity; nucleotide binding; transferase activity; |
Products Types
◆ Recombinant Protein | ||
GNE-5061H | Recombinant Human GNE Protein, GST-tagged | +Inquiry |
GNE-2260R | Recombinant Rat GNE Protein, His (Fc)-Avi-tagged | +Inquiry |
GNE-2605R | Recombinant Rat GNE Protein | +Inquiry |
GNE-3081C | Recombinant Chicken GNE | +Inquiry |
GNE-94H | Recombinant Human GNE, His-tagged | +Inquiry |
◆ Lysates | ||
GNE-5858HCL | Recombinant Human GNE 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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