Recombinant Human HSF1, GST-tagged
Cat.No. : | HSF1-13969H |
Product Overview : | Recombinant Human HSF1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 184-529a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | HSF1 heat shock transcription factor 1 [ Homo sapiens ] |
Official Symbol : | HSF1 |
Synonyms : | HSF1; heat shock transcription factor 1; heat shock factor protein 1; HSTF1; HSF 1; HSTF 1; |
Gene ID : | 3297 |
mRNA Refseq : | NM_005526 |
Protein Refseq : | NP_005517 |
MIM : | 140580 |
UniProt ID : | Q00613 |
Chromosome Location : | 8q24.3 |
Pathway : | Legionellosis, organism-specific biosystem; Legionellosis, conserved biosystem; |
Function : | protein binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; |
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HSF1-5085H | Recombinant Human HSF1 Protein, GST-tagged | +Inquiry |
HSF1-3369H | Recombinant Human HSF1 Protein (Val15-Pro288), His tagged | +Inquiry |
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◆ Lysates | ||
HSF1-339HCL | Recombinant Human HSF1 lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionHSF1 is predominantly localized in the cytoplasm of cells, and it undergoes nuclear translocation upon activation.
The role of HSF1 includes regulating protein homeostasis and the heat shock response, ensuring cellular proteostasis.
Dysregulation or abnormal expression of HSF1 is associated with conditions such as cancer, neurodegenerative disorders, and metabolic diseases.
HSF1 influences cellular processes such as apoptosis and senescence, playing a role in cell fate decisions under stress conditions.
Heat shock factor 1 (HSF1) primarily functions in cellular stress responses, orchestrating the heat shock response.
There are potential therapeutic implications related to HSF1 in diseases involving cellular stress, making it a target for drug development.
HSF1 becomes activated in response to cellular stress, such as heat shock, and it induces the expression of heat shock proteins.
Customer Reviews (3)
Write a reviewThe manufacturer's commitment to open science principles resonated with our lab's dedication to transparent research.
We valued the educational webinars and documentation that enhanced our team's proficiency in utilizing the product.
Its association with impactful research publications contributed to its reputation as a valuable scientific tool.
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