Recombinant Human IGFBP3, GST-tagged
Cat.No. : | IGFBP3-14107H |
Product Overview : | Recombinant Human IGFBP3 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Description : | This gene is a member of the insulin-like growth factor binding protein (IGFBP) family and encodes a protein with an IGFBP domain and a thyroglobulin type-I domain. The protein forms a ternary complex with insulin-like growth factor acid-labile subunit (IGFALS) and either insulin-like growth factor (IGF) I or II. In this form, it circulates in the plasma, prolonging the half-life of IGFs and altering their interaction with cell surface receptors. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 134-291a.a. |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | IGFBP3 insulin-like growth factor binding protein 3 [ Homo sapiens ] |
Official Symbol : | IGFBP3 |
Synonyms : | IGFBP3; insulin-like growth factor binding protein 3; insulin-like growth factor-binding protein 3; acid stable subunit of the 140 K IGF complex; binding protein 29; binding protein 53; BP 53; growth hormone dependent binding protein; IBP3; IGF binding protein 3; IBP-3; IGFBP-3; IGF-binding protein 3; growth hormone-dependent binding protein; BP-53; |
Gene ID : | 3486 |
mRNA Refseq : | NM_000598 |
Protein Refseq : | NP_000589 |
MIM : | 146732 |
UniProt ID : | P17936 |
Chromosome Location : | 7p13-p12 |
Pathway : | Diabetes pathways, organism-specific biosystem; Direct p53 effectors, organism-specific biosystem; Disease, organism-specific biosystem; Myometrial Relaxation and Contraction Pathways, organism-specific biosystem; Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs), organism-specific biosystem; Transcriptional misregulation in cancer, organism-specific biosystem; Transcriptional misregulation in cancer, conserved biosystem; |
Function : | insulin-like growth factor I binding; insulin-like growth factor binding; metal ion binding; protein binding; protein tyrosine phosphatase activator activity; |
Products Types
◆ Recombinant Protein | ||
IGFBP3-110I | Active Recombinant Human IGFBP3 Protein (264 aa) | +Inquiry |
IGFBP3-2039R | Recombinant Rhesus Macaque IGFBP3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP3-12H | Recombinant Human IGFBP3 Protein (28-291aa), N-His-tagged | +Inquiry |
Igfbp3-10570M | Recombinant Mouse Igfbp3 Protein, His (Fc)-Avi-tagged | +Inquiry |
IGFBP3-2678H | Recombinant Human IGFBP3 protein(121-200 aa), C-His-tagged | +Inquiry |
◆ Lysates | ||
IGFBP3-1230CCL | Recombinant Cynomolgus IGFBP3 cell lysate | +Inquiry |
IGFBP3-2927HCL | Recombinant Human IGFBP3 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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