Recombinant Human KIAA0101, His-tagged

• Cat.No.: KIAA0101-2304H
• Product Overview: Recombinant human KIAA0101 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: KIAA0101 is a PCNA-binding protein that acts as a regulator of DNA repair during DNA replication. Following DNA damage, the interaction with PCNA is disrupted, facilitating the interaction between monoubiquitinated PCNA and the translesion DNA synthesis DNA polymerase eta (POLH) at stalled replisomes, facilitating the bypass of replication-fork-blocking lesions. This protein also acts as a regulator of centrosome number.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 14.4 kDa
• Protein length: 134aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMVRTKAD SVPGTYRKVV AARAPRKVLG SSTSATNSTS VSSRKAENKY AGGNPVCVRP TPKWQKGIGE FFRLSPKDSE KENQIPEEAG SSGLGKAKRK ACPLQPDHTN DEKE
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml

Gene Information

• Gene Name: KIAA0101 KIAA0101 [ Homo sapiens ]
• Official Symbol: KIAA0101
• Synonyms: KIAA0101; PCNA-associated factor; NS5ATP9; OEATC 1; p15(PAF); HCV NS5A-transactivated protein 9; hepatitis C virus NS5A-transactivated protein 9; overexpressed in anaplastic thyroid carcinoma 1; L5; PAF; OEATC; OEATC1; p15PAF; OEATC-1; p15/PAF; FLJ58702
• Gene ID: 9768
• mRNA Refseq: NM_001029989
• Protein Refseq: NP_001025160
• MIM: 610696
• UniProt ID: Q15004
• Chromosome Location: 15q22