Active Recombinant Human IL5
Cat.No. : | IL5-99H |
Product Overview : | Recombinant Human IL5 was expressed in CHO Cells. |
- Specification
- Gene Information
- Related Products
Description : | Interleukin-5 (IL-5), produced by mast cells, T cells and eosinophils, is responsible for the activities attributed to eosinophil differentiating factor, B cell growth factor II and T cell-replacing factor (TRF). It can increase production and mobilization of eosinophils and CD34+ progenitors from the bone marrow. IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. IL-5 also promotes differentiation of basophils and primes them for histamine and leukotriene release.Recombinant Human IL-5 is homodimeric protein with molecular weight ranging from 29 to 35 kDa due to glycosylation. |
Source : | CHO Cells |
Species : | Human |
Form : | Lyophilized after extensive dialysis against PBS. |
Bio-activity : | ED50< 1 ng/ml, measured in a cell proliferation assay using tf-1 cells, corresponding to a specific activity of>1×106 units/mg. |
Molecular Mass : | ~29-35 kDa, observed by non-reducing SDS-PAGE. |
AA Sequence : | I20-S134. |
Endotoxin : | < 0.2 eu/μg, determined by lal> |
Purity : | >95% as analyzed by SDS-PAGE and HPLC. |
Storage : | Lyophilized recombinant protein remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhIL-5 should be stable up to 1 week at 4°C or up to 2 months at -20°C. |
Reconstitution : | Reconstituted in ddH2O or PBS at 100 μg/ml. |
Publication : |
Cytokine and reactivity profiles in SLE patients following anti-CD19 CART therapy (2023)
|
Gene Name : | IL5 interleukin 5 (colony-stimulating factor, eosinophil) [ Homo sapiens ] |
Official Symbol : | IL5 |
Synonyms : | IL5; interleukin 5 (colony-stimulating factor, eosinophil); interleukin-5; B cell differentiation factor I; EDF; eosinophil differentiation factor; IL 5; interleukin 5; T cell replacing factor; TRF; T-cell replacing factor; B-cell differentiation factor I; IL-5; |
Gene ID : | 3567 |
mRNA Refseq : | NM_000879 |
Protein Refseq : | NP_000870 |
MIM : | 147850 |
UniProt ID : | P05113 |
Chromosome Location : | 5q23-q31 |
Pathway : | Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Asthma, organism-specific biosystem; Asthma, conserved biosystem; Autoimmune thyroid disease, organism-specific biosystem; Autoimmune thyroid disease, conserved biosystem; Calcineurin-regulated NFAT-dependent transcription in lymphocytes, organism-specific biosystem; |
Function : | cytokine activity; growth factor activity; interleukin-5 receptor binding; protein binding; |
Products Types
◆ Recombinant Protein | ||
IL5-183M | Active Recombinant Mouse IL5 Protein | +Inquiry |
Il5-1681R | Recombinant Rat Il5 Protein, His-tagged | +Inquiry |
IL5-003D | Active Recombinant Dog IL5 Protein, His-tagged | +Inquiry |
Il5-2096M | Recombinant Mouse Il5 Protein | +Inquiry |
Il5-353I | Active Recombinant Mouse Il5 Protein (113 aa) | +Inquiry |
◆ Lysates | ||
IL5-456CCL | Recombinant Canine IL5 cell lysate | +Inquiry |
IL5-496MCL | Recombinant Mouse IL5 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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