Active Recombinant Human ITGA6
Cat.No. : | ITGA6-4110H |
Product Overview : | Recombinant Human ITGA6 was expressed in CHO Cells. |
- Specification
- Gene Information
- Related Products
Description : | The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene. |
Source : | CHO Cells |
Species : | Human |
Predicted N Terminal : | Phe24 ( alpha 6) & Asn28 ( beta 4) |
Formulation : | Lyophilized from a 0.2 µm filtered solution in PBS. |
Bio-activity : | Measured by its binding ability in a functional ELISA. When mouse Laminin I is coated at 10 µg/mL, rhIntegrin alpha 6 beta 4 binds with an apparent KD < 5 nM. |
Molecular Mass : | 104 kDa ( alpha 6) & 84.8 kDa ( beta 4) |
Purity : | >95%, by SDS-PAGE under reducing conditions and visualized by silver stain. |
Storage : | 12 months from date of receipt, 20 to 70 °C as supplied. Avoid repeated freezethaw cycles. |
Reconstitution : | Reconstitute at 200 µg/mL in sterile PBS. |
Shipping : | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Gene Name : | ITGA6 integrin, alpha 6 [ Homo sapiens (human) ] |
Official Symbol : | ITGA6 |
Synonyms : | ITGA6; integrin, alpha 6; CD49f; VLA-6; ITGA6B; integrin alpha-6; integrin alpha6B; CD49 antigen-like family member F |
Gene ID : | 3655 |
mRNA Refseq : | NM_000210 |
Protein Refseq : | NP_000201 |
MIM : | 147556 |
UniProt ID : | P23229 |
Chromosome Location : | 2q31.1 |
Pathway : | Alpha6-Beta4 Integrin Signaling Pathway; Arf6 trafficking events; Arrhythmogenic right ventricular cardiomyopathy; Assembly of collagen fibrils and other multimeric structures |
Function : | metal ion binding; protein binding |
Products Types
◆ Recombinant Protein | ||
ITGA6-06H | Recombinant Human ITGA6 Protein, N-His6ABP tagged | +Inquiry |
ITGA6-2135R | Recombinant Rhesus Macaque ITGA6 Protein, His (Fc)-Avi-tagged | +Inquiry |
Itga6-1698M | Recombinant Mouse Itga6 Protein, His-tagged | +Inquiry |
Itga6-1699M | Recombinant Mouse Itga6 Protein, His-tagged | +Inquiry |
ITGA6-2612H | Recombinant Human ITGA6 Protein, MYC/DDK-tagged | +Inquiry |
◆ Lysates | ||
ITGA6-5131HCL | Recombinant Human ITGA6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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