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Recombinant Human FASLG Protein, His-tagged

Cat.No. : FASLG-151H
Product Overview : Recombinant Human Fas ligand(FASLG), transcript variant 1(NM_000639), with a His tag, was expressed in human cells.
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  • Gene Information
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Description : This gene is a member of the tumor necrosis factor superfamily. The primary function of the encoded transmembrane protein is the induction of apoptosis triggered by binding to FAS. The FAS/FASLG signaling pathway is essential for immune system regulation, including activation-induced cell death (AICD) of T cells and cytotoxic T lymphocyte induced cell death. It has also been implicated in the progression of several cancers. Defects in this gene may be related to some cases of systemic lupus erythematosus (SLE). Alternatively spliced transcript variants have been described.
Source : Human Cells
Species : Human
Tag : His
Form : Purified protein formulated in a sterile solution of TBS buffer, pH7.238, without any preservatives.
Molecular Mass : 31.3 kDa
Endotoxin : Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
Purity : >90% by SDS-PAGE gel and Coomassie Blue staining
Applications : Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.
Gene Name : FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ]
Official Symbol : FASLG
Synonyms : FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1;
Gene ID : 356
mRNA Refseq : NM_000639
Protein Refseq : NP_000630
MIM : 134638
UniProt ID : P48023

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there diagnostic tests that measure FASLG levels in clinical settings? 06/27/2019

Yes, there are diagnostic tests that measure FASLG levels, which can provide insights into immune function and disease processes.

In what ways can the FASLG protein be targeted for therapeutic purposes? 11/29/2018

The FASLG protein can be targeted for therapeutic purposes in cancer treatment and autoimmune disease management.

How is the FASLG protein involved in the pathogenesis of liver diseases? 09/17/2018

Dysregulation of FASLG expression can contribute to liver injury and the progression of liver diseases such as hepatitis and liver fibrosis.

How does the FASLG protein contribute to the pathogenesis of inflammatory bowel disease? 01/11/2018

Dysregulation of FASLG expression can impact intestinal immune homeostasis and contribute to the pathogenesis of inflammatory bowel disease.

What role does the FASLG protein play in organ transplantation? 01/17/2016

FASLG is involved in the regulation of immune responses to transplanted organs, and its dysregulation can impact transplant outcomes.

Customer Reviews (3)

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Reviews
06/06/2021

    The outstanding level of customer service adds extra reassurance and confidence in using the FASLG protein for my scientific investigations.

    06/20/2018

      the manufacturer of FASLG provides exceptional technical support, offering valuable assistance in troubleshooting and experimental design.

      08/28/2017

        The FASLG protein surpasses expectations in terms of quality and will undoubtedly fulfill my experimental requirements.

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