Recombinant Human Hepatocyte Growth Factor (Hepapoietin A; Scatter factor)
Cat.No. : | HGF-123H |
Product Overview : | Recombinant Human Hepatocyte Growth Factor produced inCHOis a heterodimer, non-glycosylated, polypeptide chain consisting a α-chain of 463 amino acids and -chain of 234 having a total molecular mass of 80017 Dalton. The HGF is purified by proprietary chromatographic techniques. |
- Specification
- Gene Information
- Related Products
Cat. No. : | HGF-123H |
Description : | Hepatocyte Growth Factor (HGF) is a multifunctional growth factor which regulates both cell growth and cell motility. It exerts a strong mitogenic effect on hepatocytes and primary epithelial cells. HGF synergizes with Interleukin-3 and GM-CSF to stimulate colony formation of hematopoietic progenitor cells in vitro and may, therefore, also modulate hematopoiesis. |
Source : | Chinese Hamster Ovary Cells |
Physical Appearance : | Sterile Filtered White lyophilized (freeze-dried) powder. |
Purity : | Greater than 97.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. |
Formulation : | The protein was lyophilized from a concentrated (1mg/ml) solution containing Phosphate-Buffered Saline pH= 7.4 containing 0.05% Tween 20. |
Solubility : | It is recommended to reconstitute the lyophilized Hepatocyte Growth Factor in sterile 18MΩ-cm H2O not less than 100µg/ml, which can then be further diluted to other aqueous solutions. |
Amino Acid Sequence : | Agrees with the sequence of native human HGF. |
Biological Activity : | The ED50, calculated by the dose-dependant proliferation of monkey 4MBr-5 indicator cells was found to be 20-40 ng/ml. |
Protein Content : | Protein quantitation was carried out by two independent methods: 1.UV spectroscopy at 280 nm using the absorbency value of 1.83 as the extinction coefficient for a 0.1% (1mg/ml) solution. This value is calculated by the PC GENE computer analysis program of protein sequences (IntelliGenetics). 2. Analysis by RP-HPLC, using a calibrated solution of HGF as a Reference Standard. |
Storage : | Lyophilized Hepatocyte Growth Factor although stable at room temperature for 3 weeks, should be stored desiccated below -18°C. Upon reconstitution HGF should be stored at 4°Cbetween 2-7 days and for future use below -18°C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles. |
Gene Name : | HGF hepatocyte growth factor (hepapoietin A; scatter factor) [ Homo sapiens ] |
Synonyms : | HGF; hepatocyte growth factor (hepapoietin A; scatter factor); SF; HGFB; HPTA; F-TCF; DFNB39; scatter factor; hepatopoietin A; OTTHUMP00000206710; lung fibroblast-derived mitogen; fibroblast-derived tumor cytotoxic factor; DFNB39; deafness, autosomal recessive 39; fibroblast-derived tumor cytotoxic factor; scatter factor; Hepatocyte growth factor; SF; Hepatocyte growth factor alpha chain; Hepatocyte growth factor beta chainen |
Gene ID : | 3082 |
mRNA Refseq : | NM_000601 |
Protein Refseq : | NP_000592 |
MIM : | 142409 |
UniProt ID : | P14210 |
Chromosome Location : | 7q21.1 |
Pathway : | Cytokine-cytokine receptor interaction; Focal adhesion; Melanoma; Pathways in cancer; Renal cell carcinoma; Hemostasis |
Function : | catalytic activity; growth factor activity; protein binding; protein heterodimerization activity; serine-type endopeptidase activity |
Products Types
◆ Recombinant Protein | ||
HGF-114H | Recombinant Active Human HGF Protein, Tag Free | +Inquiry |
Hgf-257M | Recombinant Mouse Hgf Protein | +Inquiry |
HGF-13H | Active Recombinant Human HGF Propeptide Protein | +Inquiry |
HGF-3402M | Active Recombinant Mouse HGF protein(Met1-Leu728) | +Inquiry |
HGF-18H | Active Recombinant Human HGF Protein, Animal Free | +Inquiry |
◆ Native Protein | ||
HGF-29231TH | Native Human HGF | +Inquiry |
HGF-38P | Native Porcine HGF | +Inquiry |
◆ Lysates | ||
HGF-1233RCL | Recombinant Rat HGF cell lysate | +Inquiry |
HGF-001HCL | Recombinant Human HGF cell lysate | +Inquiry |
HGF-1210MCL | Recombinant Mouse HGF cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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