Creative BioMart to Present at
                        BIO-Europe Spring Creative BioMart to Present at AACR Annual Meeting|Apr. 5-10, 2024|Booth #2953

Recombinant Mouse FLT3 protein, His-tagged

Cat.No. : FLT3-303M
Product Overview : Recombinant Mouse FLT3 protein(EDL05832.1)(Met1-Ser544), fused with His tag, was expressed in HEK293.
  • Specification
  • Gene Information
  • Related Products
Source : HEK293
Species : Mouse
Tag : His
Form : Lyophilized from sterile PBS, pH 7.4.Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Molecular Mass : The recombinant mouse FLT3 comprises 528 amino acids and has a predicted molecular mass of 59.5 kDa. As a result of glycosylation, it migrates as an approximately 88 kDa band in SDS-PAGE under reducing conditions.
Protein Length : Met1-Ser544
Endotoxin : < 1.0 EU per μg of the protein as determined by the LAL method
Purity : > 75 % as determined by SDS-PAGE
Storage : Samples are stable for up to twelve months from date of receipt at -20°C to -80°C
Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
Gene Name : Flt3 FMS-like tyrosine kinase 3 [ Mus musculus ]
Official Symbol : FLT3
Synonyms : FLT3; FMS-like tyrosine kinase 3; receptor-type tyrosine-protein kinase FLT3; FL cytokine receptor; fetal liver kinase 2; tyrosine-protein kinase FLT3; tyrosine-protein kinase receptor flk-2; Flk2; Ly72; wmfl; CD135; Flk-2; Flt-3; B230315G04; MGC124377; MGC124378;
Gene ID : 14255
mRNA Refseq : NM_010229
Protein Refseq : NP_034359

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

Inquiry

  • Q&As
  • Reviews

Q&As (7)

Ask a question
How is FLT3 implicated in acute myeloid leukemia (AML)? 12/24/2021

FLT3 is frequently mutated in AML, contributing to uncontrolled cell growth and poor prognosis.

In which cells or tissues is FLT3 predominantly expressed? 07/08/2021

FLT3 is predominantly expressed in hematopoietic stem cells and progenitor cells.

How does FLT3 contribute to hematopoiesis? 03/15/2021

It is essential for hematopoiesis, particularly in the proliferation of early progenitor cells.

Are there therapeutic strategies targeting FLT3 for disease treatment? 08/01/2020

Therapeutic strategies include FLT3 inhibitors, showing effectiveness in treating AML patients with FLT3 mutations.

What is the primary biological function of FLT3 in cells? 06/27/2020

FLT3 is a receptor tyrosine kinase that plays a crucial role in cell survival, proliferation, and differentiation.

What role does FLT3 play in the proliferation and differentiation of hematopoietic stem cells? 07/14/2019

It stimulates the proliferation and differentiation of hematopoietic stem cells, guiding their development into various blood cell types.

What are the common mutations found in FLT3 associated with diseases? 04/05/2019

Common mutations include internal tandem duplications (ITD) and tyrosine kinase domain (TKD) mutations, leading to constitutive activation of FLT3.

Customer Reviews (3)

Write a review
Reviews
08/01/2021

    Excellent product, great price.

    12/22/2020

      Satisfied, will order again.

      09/14/2020

        Quick response, helpful service.

        Ask a Question for All FLT3 Products

        Required fields are marked with *

        My Review for All FLT3 Products

        Required fields are marked with *

        0

        Inquiry Basket

        cartIcon
        logo

        FOLLOW US

        Terms and Conditions        Privacy Policy

        Copyright © 2024 Creative BioMart. All Rights Reserved.

        Contact Us

        • /

        Stay Updated on the Latest Bioscience Trends