similar : |
TNFRSF6B |
Alias : |
TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1; |
Source : |
Insect Cells |
Species : |
Human |
Conjugate : |
C-hFc |
Tag : |
C-hFc |
Protein length : |
Met1-His300 |
Form : |
Lyophilized from sterile 100mM Glycine, 10mM NaCl, pH 7.0. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Bioactivity : |
Measured by its ability to inhibit Fas Ligand induced apoptosis of Jurkat human acute T cell leukemia cells. The ED50 for this effect is typically 0.5-3 μg/mL in the presence of 200 ng/mL recombinant human Fas ligand. |
MolecularMass : |
The recombinant human DCR3/Fc is a disulfide-linked homodimer. The reduced monomer comprises 508 amino acids and has a predicted molecular mass of 56.4 kDa. The apparent molecular mass of the protein is approximately 65 kDa in SDS-PAGE under reducing conditions. |
Endotoxin : |
< 1.0 EU per μg of the protein as determined by the LAL method |
Purity : |
> 85 % as determined by SDS-PAGE |
Storage : |
Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : |
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
GeneName : |
TNFRSF6B tumor necrosis factor receptor superfamily, member 6b, decoy [ Homo sapiens ] |
GeneNameWeblink : |
8771 |
OfficialSymbol : |
TNFRSF6B |
OfficialSymbolWeblink : |
8771 |
GeneID : |
8771 |
GeneIDWeblink : |
8771 |
mRNARefseq : |
NM_003823 |
mRNARefseqWeblink : |
NM_003823.3 |
ProteinRefseqWeblink : |
NP_003814.1 |
MIMWeblink : |
603361 |
UniProtID : |
O95407 |
UniProtIDWeblink : |
O95407 |
Synonyms : |
TNFRSF6B; tumor necrosis factor receptor superfamily, member 6b, decoy; tumor necrosis factor receptor superfamily member 6B; DcR3; DCR3; M68; TR6; decoy receptor 3; decoy receptor for Fas ligand; M68E; DJ583P15.1.1; |
MIM : |
603361 |