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Recombinant Cynomolgus TFRC, His tagged

Cat.No. : TFRC-132C
Product Overview : Recombinant Cynomolgus TFRC (NP_001244232.1) (Cys89-Phe760), fused with a polyhistidine tag at the N-terminus, was produced in Human Cells.
  • Specification
  • Gene Information
  • Related Products
Source : Human Cells
Species : Cynomolgus
Tag : His
Predicted N Terminal : His
Form : Lyophilized from sterile PBS, pH 7.4.Normally 5 % - 8 % trehalose and mannitol are added as protectants before lyophilization.
Molecular Mass : The recombinant cynomolgus TFRC comprises 692 amino acids and has a calculated molecular mass of 77.6 KDa. The apparent molecular mass of it is approximately 65-85 KDa in SDS-PAGE under reducing conditions.
Endotoxin : < 1.0 eu per μg of the protein as determined by the LAL method.
Purity : >95 % as determined by SDS-PAGE
Stability : Samples are stable for up to twelve months from date of receipt at -70oC.
Storage : Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
Reconstitution : It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents.
Gene Name : TFRC transferrin receptor (p90, CD71) [ Macaca fascicularis (crab-eating macaque) ]
Official Symbol : TFRC
Gene ID : 102136007
mRNA Refseq : XM_005545258
Protein Refseq : XP_005545315
Chromosome Location : 2

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Can TFRC be used to develop targeted drug delivery systems? 09/13/2022

Yes, TFRC's presence on cell surfaces has been exploited for the development of targeted drug delivery systems, especially for delivering drugs to cancer cells.

Are there any therapies that target TFRC in cancer treatment? 11/17/2020

Yes, some experimental therapies aim to target TFRC on cancer cells, such as antibody-drug conjugates (ADCs) and small-molecule inhibitors.

Are there any clinical conditions associated with TFRC protein dysregulation? 09/19/2017

Yes, dysregulation of TFRC expression or function can be associated with various medical conditions, including anemia, cancer, and neurodegenerative diseases.

How is TFRC protein studied in clinical research and diagnostics? 10/03/2016

Researchers use techniques like immunohistochemistry and molecular assays to study TFRC expression levels in patient samples. This helps in diagnosis and prognosis.

How can TFRC be relevant in the treatment of iron-deficiency anemia? 01/02/2016

Understanding TFRC expression in the context of anemia can help identify the underlying causes and guide treatment strategies to improve iron uptake.

Customer Reviews (3)

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Reviews
09/06/2021

    In addition to the advantages of GAD1 protein itself, the manufacturer can play a crucial role in supporting the research efforts.

    04/19/2018

      This quality control is essential for obtaining reliable and reproducible data, as any variability in protein quality can introduce confounding factors into experiments.

      01/27/2017

        This versatility enables researchers to explore GAD1's function and role in a range of biological processes, making it a valuable tool across diverse research fields.

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