| Description : |
Amphoterin-Induced Protein 2 (AMIGO2) is a single-pass type I membrane protein which belongs to the AMIGO family of immunoglobulin superfamily. Mature AMIGO2 contains an Ig-like C2-type (immunoglobulin-like) domain, 6 LRR (leucine-rich) repeats, a LRRCT domain, as well as a LRRNT domain. AMIGO2 is mainly expressed in in breast, ovary, cervix, and uterus, although lower in lung, colon, and rectum. AMIGO2 required for depolarization-dependent survival of cultured cerebellar granule neurons. AMIGO2 may mediate homophilic as well as heterophilic cell-cell interaction with AMIGO1 or AMIGO3. AMIGO2 may contribute to signal transduction through its intracellular domain, and may be required for tumorigenesis of a subset of gastric adenocarcinomas. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
His |
| Form : |
Lyophilized from a 0.2 μM filtered solution of 20mM PB, 150mM NaCl, pH 7.2 |
| AA Sequence : |
VCPTACICATDIVSCTNKNLSKVPG NLFRLIKRLDLSYNRIGLLDSEWIP VSFAKLNTLILRHNN ITSISTGSFSTTPNLKCLDLSSNKL KTVKNAVFQELKVLEVLLLYNNHIS YLDPSAFGGLSQLQK LYLSGNFLTQFPMDLYVGRFKLAEL MFLDVSYNRIPSMPMHHINLVPGKQ LRGIYLHGNPFVCDC SLYSLLVFWYRRHFSSVMDFKNDYT CRLWSDSRHSRQVLLLQDSFMNCSD SIINGSFRALGFIHE AQVGERLMVHCDSKTGNANTDFIWV GPDNRLLEPDKEMENFYVFHNGSLV IESPRFEDAGVYSCI AMNKQRLLNETVDVTINVSNFTVSR SHAHVDHHHHHH |
| Endotoxin : |
Less than 0.1 ng/μg (1 IEU/μg). |
| Purity : |
Greater than 95% as determined by SEC-HPLC and reducing SDS-PAGE. |
| Storage : |
Lyophilized protein should be stored at Reconstituted protein solution can be stored at 4-7°C for 2-7 days.Aliquots of reconstituted samples are stable at |
| Reconstitution : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting.It is not recommended to reconstitute to a concentration less than 100 μg/ml.Dissolve the lyophilized protein in 1X PBS.Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
