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Recombinant Human PACSIN1, His-tagged

Cat.No. : PACSIN1-166H
Product Overview : Recombinant Human Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1/PACSIN1 is produced by our mammalian expression system in human cells. The target protein is expressed with sequence (Met1-Ile444) of Human PACSIN1 fused with a 6His tag at the C-terminus.
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Description : Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC).
Source : HEK293
Species : Human
Tag : His
AA Sequence : MSSSYDEASLAPEETTDSFWEVGNY KRTVKRIDDGHRLCNDLMNCVQERA KIEKAYGQQLTDWAK RWRQLIEKGPQYGSLERAWGAIMTE ADKVSELHQEVKNNLLNEDLEKVKN WQKDAYHKQIMGGFK ETKEAEDGFRKAQKPWAKKMKELEA AKKAYHLACKEEKLAMTREMNSKTE QSVTPEQQKKLQDKV DKCKQDVQKTQEKYEKVLEDVGKTT PQYMENMEQVFEQCQQFEEKRLVFL KEVLLDIKRHLNLAE NSSYIHVYRELEQAIRGADAQEDLR WFRSTSGPGMPMNWPQFEEWNPDLP HTTTKKEKQPKKAEG VALTNATGAVESTSQAGDRGSVSSY DRGQPYATEWSDDESGNPFGGSETN GGANPFEDDSKGVRV RALYDYDGQEQDELSFKAGDELTKL GEEDE QGWCRGRLDSGQLGLYPANYVEAIV DHHHHHH
Endotoxin : Less than 0.1 ng/μg (1 IEU/μg).
Purity : Greater than 95% as determined by reducing SDS-PAGE.
Gene Name : PACSIN1 protein kinase C and casein kinase substrate in neurons 1 [ Homo sapiens ]
Official Symbol : PACSIN1
Synonyms : PACSIN1; protein kinase C and casein kinase substrate in neurons 1; protein kinase C and casein kinase substrate in neurons protein 1; SDPI; syndapin I; KIAA1379;
Gene ID : 29993
mRNA Refseq : NM_001199583
Protein Refseq : NP_001186512
MIM : 606512
UniProt ID : Q9BY11
Chromosome Location : 6p21.3
Function : cytoskeletal protein binding; protein kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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