Recombinant Mouse Il16 protein
Cat.No. : | Il16-548M |
Product Overview : | Recombinant Mouse Il16 protein was expressed in Escherichia coli. |
- Specification
- Gene Information
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Description : | Interleukin-16 (IL-16) is also called lymphocyte chemoattractant factor (LCF) and it is mostly secreted by lymphocytes, epithelial cells, eosinophils, and CD8+ T cells. It has many functions including induction of the IL-2Rα on T cells, suppression of human immunodeficiency virus (HIV) replication, inhibition of T-cell antigen receptor/CD3 mediated T-cell stimulation in mixed lymphocyte reactions and so on. It signals through CD4 receptor. Furthermore, recombinant murine interleukin-16 contains 118 amino acid residues and it shares about 85 % a.a. sequence identity with different isoforms of human IL-16. |
Source : | E.coli |
Species : | Mouse |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
Bio-activity : | Fully biologically active when compared to standard. The biological activity determined by a chemotaxis bioassay using human peripheral T lymphocytes is in a concentration range of 1.0-100 ng/ml. |
Molecular Mass : | Approximately 12.2 kDa, a single non-glycosylated polypeptide chain containing 118 amino acids. |
Protein length : | 118 |
AA Sequence : | SAASASAASDISVESKEATVCTVTL EKTSAGLGFSLEGGKGSLHGDKPLT INRIFKGTEQGEMVQPGDEILQLAG TAVQGLTRFEAWNVIKALPDGPVTI VIRRTSLQCKQTTASADS |
Endotoxin : | Less than 1 EU/µg of rMuIL-16 as determined by LAL method. |
Purity : | >98% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Gene Name : | Il16 |
Official Symbol : | Il16 |
Synonyms : | IL16; interleukin 16; pro-interleukin-16; mKIAA4048; KIAA4048; |
Gene ID : | 16170 |
mRNA Refseq : | NM_010551 |
Protein Refseq : | NP_034681 |
UniProt ID : | O54824 |
Products Types
◆ Recombinant Protein | ||
IL16-1007C | Recombinant Chicken IL16 Protein, His-tagged | +Inquiry |
Il16-1239M | Recombinant Mouse Il16 Protein, MYC/DDK-tagged | +Inquiry |
IL16-2055R | Recombinant Rhesus Macaque IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
IL16-2865H | Recombinant Human IL16 protein(1211-1330 aa), C-His-tagged | +Inquiry |
IL16-1165H | Recombinant Human IL16 Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Native Protein | ||
IL16-29736TH | Native Human IL16 | +Inquiry |
◆ Lysates | ||
IL16-5245HCL | Recombinant Human IL16 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (10)
Ask a questionLeukocyte migration assays measure IL16's chemotactic impact on cells.
Flow cytometry and qPCR assess T cell activation markers affected by IL16.
Gene expression arrays reveal IL16's influence on inflammatory gene profiles.
RNA interference used to knock down IL16 expression in cell lines.
Experimental setup for studying IL16's modulation of HIV infection involves viral assays.
Binding affinity of IL16 to CD4 receptors determined through SPR or ITC.
Flow cytometry and confocal microscopy visualize IL16's cellular localization.
Mouse models and clinical samples aid in understanding IL16's role in autoimmunity.
ELISA quantifies secreted IL16 levels from cell culture supernatants.
Strategies like animal models and patient samples explore IL16's role in allergies.
Customer Reviews (3)
Write a reviewSuitable for ELISA.
High specificity in ELISA.
Potent in chemotaxis studies.
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