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Active Recombinant Human AXL (R499C), GST-tagged

Cat.No. : AXL-202H
Product Overview : Recombinant human AXL (R499C) (473-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag.
  • Specification
  • Gene Information
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Description : AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase which is a member of the TAM (TYRO3/AXL/MER) receptor tyrosine kinase subfamily. AXL represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats and Axl transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding.
Source : Sf9 insect cells using baculovirus
Species : Human
Tag : GST
Form : Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol.
Bio-activity : The specific activity of AXL (R499C) was determined to be 3 nmol /min/mg
Molecular Mass : ~76 kDa
Purity : >85% by densitometry
Applications : Kinase Assay, Western Blot
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 μg/μl
Gene Name : AXL AXL receptor tyrosine kinase [ Homo sapiens ]
Official Symbol : AXL
Synonyms : AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene;
Gene ID : 558
mRNA Refseq : NM_001699
Protein Refseq : NP_001690
MIM : 109135
UniProt ID : P30530
Chromosome Location : 19q13.1
Function : ATP binding; nucleotide binding; protein heterodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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