Active Recombinant Human AXL (R499C), GST-tagged
Cat.No. : | AXL-202H |
Product Overview : | Recombinant human AXL (R499C) (473-end) was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. |
- Specification
- Gene Information
- Related Products
Description : | AXL, a transforming gene isolated from primary human myeloid leukemia cells, encodes a novel receptor tyrosine kinase which is a member of the TAM (TYRO3/AXL/MER) receptor tyrosine kinase subfamily. AXL represents a unique structure of the extracellular region that juxtaposes IgL and FNIII repeats and Axl transduces signals from the extracellular matrix into the cytoplasm by binding growth factors like vitamin K-dependent protein growth-arrest-specific gene 6. AXL is involved in the stimulation of cell proliferation and can also mediate cell aggregation by homophilic binding. |
Source : | Sf9 insect cells using baculovirus |
Species : | Human |
Tag : | GST |
Form : | Recombinant protein stored in 50mM Tris-HCl, pH 7.5, 150mM NaCl, 10mM glutathione, 0.1mM EDTA, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Bio-activity : | The specific activity of AXL (R499C) was determined to be 3 nmol /min/mg |
Molecular Mass : | ~76 kDa |
Purity : | >85% by densitometry |
Applications : | Kinase Assay, Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | AXL AXL receptor tyrosine kinase [ Homo sapiens ] |
Official Symbol : | AXL |
Synonyms : | AXL; AXL receptor tyrosine kinase; tyrosine-protein kinase receptor UFO; JTK11; UFO; AXL oncogene; oncogene AXL; AXL transforming sequence/gene; |
Gene ID : | 558 |
mRNA Refseq : | NM_001699 |
Protein Refseq : | NP_001690 |
MIM : | 109135 |
UniProt ID : | P30530 |
Chromosome Location : | 19q13.1 |
Function : | ATP binding; nucleotide binding; protein heterodimerization activity; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
◆ Recombinant Protein | ||
AXL-2918H | Recombinant Human AXL Protein(26-451aa(D266N)), His-tagged | +Inquiry |
Axl-813H | Recombinant Human Axl Protein | +Inquiry |
Axl-10522M | Recombinant Mouse Axl Protein, His (Fc)-Avi-tagged | +Inquiry |
AXL-167H | Recombinant Human AXL Protein, His (Fc)-Avi-tagged | +Inquiry |
AXL-088H | Recombinant Human AXL Protein, DYKDDDDK-tagged | +Inquiry |
◆ Lysates | ||
AXL-2281HCL | Recombinant Human AXL cell lysate | +Inquiry |
AXL-2476MCL | Recombinant Mouse AXL cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (0)
Ask a questionAsk a Question for All AXL Products
Required fields are marked with *
My Review for All AXL Products
Required fields are marked with *
0
Inquiry Basket