Recombinant Human UBE2D3, His-tagged
Cat.No. : | UBE2D3-205H |
Product Overview : | Recombinant full length human UBE2D3 (UBCH5C) was expressed in E. coli cells using an N-terminal His tag. |
- Specification
- Gene Information
- Related Products
Description : | UBE2D3 also known as UBCH5C or ubiquitin-conjugating enzyme E2D 3 is a member of the E2 ubiquitin-conjugating enzyme family which is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. UBE2D3 is involved in RA-induced cell cycle arrest and as a mediator of all-trans retinoic acid-induced cell growth arrest in human acute promyelocytic NB4 cells. UBE2D3 functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase and is critical for normal cellular, tissue, and organismal physiology. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Recombinant protein stored in 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol. |
Molecular Mass : | ~17 kDa |
Purity : | >95% by densitometry |
Applications : | Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.1 μg/μl |
Gene Name : | UBE2D3 ubiquitin-conjugating enzyme E2D 3 [ Homo sapiens ] |
Official Symbol : | UBE2D3 |
Synonyms : | UBE2D3; ubiquitin-conjugating enzyme E2D 3; ubiquitin conjugating enzyme E2D 3 (homologous to yeast UBC4/5) , ubiquitin conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2 D3; UbcH5C; E2(17)KB 3; ubiquitin-protein ligase D3; ubiquitin carrier protein D3; ubiquitin-conjugating enzyme E2(17)KB 3; ubiquitin-conjugating enzyme E2-17 kDa 3; ubiquitin-conjugating enzyme E2D 3 (UBC4/5 homolog, yeast); ubiquitin-conjugating enzyme E2D 3 (homologous to yeast UBC4/5); UBC4/5; UBCH5C; E2(17)KB3; MGC5416; MGC43926; |
Gene ID : | 7323 |
mRNA Refseq : | NM_003340 |
Protein Refseq : | NP_003331 |
MIM : | 602963 |
UniProt ID : | P61077 |
Chromosome Location : | 4q24 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; BMP Signalling Pathway, organism-specific biosystem; Canonical NF-kappaB pathway, organism-specific biosystem; Class I MHC mediated antigen processing & |
Function : | ATP binding; acid-amino acid ligase activity; ligase activity; nucleotide binding; protein binding; ubiquitin-protein ligase activity; |
Products Types
◆ Recombinant Protein | ||
UBE2D3-4869R | Recombinant Rhesus Macaque UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D3-2004H | Recombinant Human UBE2D3 Protein, His-tagged | +Inquiry |
UBE2D3-6053R | Recombinant Rat UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
UBE2D3-816C | Recombinant Cynomolgus Monkey UBE2D3 Protein, His (Fc)-Avi-tagged | +Inquiry |
Ube2d3-6784M | Recombinant Mouse Ube2d3 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
UBE2D3-586HCL | Recombinant Human UBE2D3 293 Cell Lysate | +Inquiry |
UBE2D3-585HCL | Recombinant Human UBE2D3 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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