Recombinant Human MAPT
Cat.No. : | MAPT-218H |
Product Overview : | Recombinant full-length human tag-free Tau-316 was expressed in E. coli cells. |
- Specification
- Gene Information
- Related Products
Description : | Tau-316 encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. Tau-316 transcripts are differentially expressed in the nervous system, depending on stage of neuronal maturation and neuron type. Tau-316 gene mutations have been associated with several neurodegenerative disorders such as Alzheimer"s disease, Pick"s disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy. |
Source : | E. coli |
Species : | Human |
Form : | Recombinant protein stored in 50mM Tis-HCl, pH 7.5, 150mM NaCl, 0.25mM DTT, 0.1mM PMSF, 25% glycerol. |
Molecular Mass : | ~39 kDa (32.9kDa by MW calculation) |
Purity : | >90% by densitometry |
Applications : | Kinase Assay, Western Blot |
Storage : | Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles. |
Concentration : | 0.2 μg/μl |
Gene Name : | MAPT microtubule-associated protein tau [ Homo sapiens ] |
Official Symbol : | MAPT |
Synonyms : | MAPT; microtubule-associated protein tau; DDPAC, MAPTL; FLJ31424; FTDP 17; G protein beta1/gamma2 subunit interacting factor 1; MGC138549; microtubule associated protein tau; isoform 4; MSTD; MTBT1; MTBT2; PPND; tau; TAU; PHF-tau; paired helical filament-tau; neurofibrillary tangle protein; microtubule-associated protein tau, isoform 4; G protein beta1/gamma2 subunit-interacting factor 1; DDPAC; MAPTL; FTDP-17; |
Gene ID : | 4137 |
mRNA Refseq : | NM_001123066 |
Protein Refseq : | NP_001116538 |
MIM : | 157140 |
UniProt ID : | P10636 |
Chromosome Location : | 17q21 |
Pathway : | Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic cleavage of cellular proteins, organism-specific biosystem; Apoptotic executionphase, organism-specific biosystem; Caspase-mediated cleavage of cytoskeletal proteins, organism-specific biosystem; IL-6 Signaling Pathway, organism-specific biosystem; |
Function : | SH3 domain binding; apolipoprotein E binding; enzyme binding; lipoprotein particle binding; microtubule binding; protein binding; structural constituent of cytoskeleton; |
Products Types
◆ Recombinant Protein | ||
MAPT-02C | Recombinant Cynomolgus MAPT Protein, His tagged | +Inquiry |
Mapt-3953M | Recombinant Mouse Mapt Protein, Myc/DDK-tagged | +Inquiry |
MAPT-2892H | Recombinant Human MAPT protein(1-441 aa)(acetyl K274), C-His-tagged | +Inquiry |
MAPT-528H | Recombinant Human MAPT protein(Ala2-Leu352), His-tagged | +Inquiry |
MAPT-2893H | Recombinant Human MAPT protein(1-441 aa)(acetyl K281), C-His-tagged | +Inquiry |
◆ Lysates | ||
MAPT-4478HCL | Recombinant Human MAPT 293 Cell Lysate | +Inquiry |
MAPT-4477HCL | Recombinant Human MAPT 293 Cell Lysate | +Inquiry |
MAPT-4476HCL | Recombinant Human MAPT 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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