Active Native Human Glutamate Pyruvate Transaminase

• Cat.No.: GPT-187H
• Product Overview: Purified Native Human Heart Glutamate Pyruvate Transaminase. CAS Number: 9000-86-6; E.C. Number: 2.6.1.2

Specification

• Description: Acute levels of ALT in your blood is a possible indicator of hepatitis and liver injury due to alcohol and drugs or liver disorder due to jaundice. ALT is often measured along with AST.Human Alanine transaminase(ALT) is an enzyme that catalyzes the reversible transfer of an amino group from alanine to a-ketoglutarate and is found in serum and in various bodily tissues but is most commonly associated with the liver.
• Source: Human Heart
• Species: Human
• Form: Lyophilized from tris chloride, EDTA, DTT, a-ketoglutarate and pyridoxal-5-phosphate, pH 7.0
• Bio-activity: >10 U/mg protein
• Storage: Store at -20°C.
• Concentration: >0.4 mg protein/mg

Gene Information

• Gene Name: GPT glutamic-pyruvate transaminase (alanine aminotransferase) [ Homo sapiens ]
• Official Symbol: GPT
• Synonyms: GPT; glutamic-pyruvate transaminase (alanine aminotransferase); alanine aminotransferase 1; ALT1; GPT1; GPT 1; glutamic-alanine transaminase 1; glutamic--alanine transaminase 1; glutamic--pyruvic transaminase 1; glutamate pyruvate transaminase 1; AAT1
• Gene ID: 2875
• mRNA Refseq: NM_005309
• Protein Refseq: NP_005300
• MIM: 138200
• UniProt ID: P24298
• Chromosome Location: 8q24.2-qter
• Pathway: Alanine and aspartate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, organism-specific biosystem; Alanine, aspartate and glutamate metabolism, conserved biosystem; Amino acid synthesis and interconversion (transamination), organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem
• Function: 1-aminocyclopropane-1-carboxylate synthase activity; L-alanine:2-oxoglutarate aminotransferase activity; L-alanine:2-oxoglutarate aminotransferase activity; pyridoxal phosphate binding; transaminase activity