Address: 45-1 Ramsey Road, Shirley, NY 11967, USA    USA: 1-631-559-9269  1-631-448-7888   Fax: 1-631-938-8127  Europe: 44-207-097-1828   Email: info@creative-biomart.com
Home > Products > Recombinant Proteins > Recombinant Human CD40, Fc-tagged

Recombinant Human CD40, Fc-tagged

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Fc(11)
Fc-His(3)
Hi & Fc & Avi(1)
His(17)
His & Avi(1)
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Human(6)
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Cat.No.:
CD40-144H
Product Overview:
The Fc portion of human IgG1 is fused to the C-terminus of human CD40 (aa 21-193).
Description:
CD40 belongs to the TNF-receptor superfamily and is essential in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development and germinal center formation. The interaction of CD40-CD40L is necessary for amyloid-β-induced microglial activation, and thus is thought to be an early event in Alzheimer disease pathogenesis. CD40 is constitutively expressed by antigen presenting cells, including dendritic cells, B cells and macrophages. Consistent with its widespread expression on normal cells, CD40 is also expressed on a wide range of tumor cells, including non-Hodgkins and Hodgkins lymphomas, myeloma and some carcinomas including nasopharynx, bladder, cervix, kidney and ovary.
Source:
HEK293 Cells
Species:
Human
Tag:
Fc
Form:
Lyophilized. Contains PBS.
Bio-activity:
Blocks the binding of CD40L to CD40.
Molecular Mass:
~54kDa (SDS-PAGE)
Purity:
≥95% (SDS-PAGE)
Stability:
Stable for at least 6 months after receipt when stored at -20°C.
Storage:
Short Term Storage: +4°C; Long Term Storage: -20°C. After receipt, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions.
Concentration:
1mg/ml after reconstitution.


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Note: There will be extra charge for optional service!
Optional requirements on this protein +Expand
C-fusion   N-fusion  Non-tagged
His   GST  Fc  Others
<1.0 eu/μg   <0.1 eu/μg  <0.01 eu/μg  Not required
Monomer Isolation   Dimer Isolation   Not required
>80% by SDS-PAGE   >90% by SDS-PAGE  >95% by SDS-PAGE  Others
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45-1 Ramsey Road, Shirley, NY 11967, USA
USA: 1-631-559-9269  1-631-448-7888
Europe: 44-207-097-1828
FAX: 1-631-938-8127
EMAIL: info@creative-biomart.com

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