Active Recombinant Human FASLG, Fc-tagged
Cat.No. : | FASLG-245H |
Product Overview : | Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1. |
- Specification
- Gene Information
- Related Products
Description : | Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development. |
Source : | HEK293 Cells |
Species : | Human |
Tag : | Fc |
Form : | Lyophilized. Contains PBS. |
Bio-activity : | Induces apoptosis of human Jurkat T cells at a concentration of<0.2ng l.>0.2ng> |
Molecular Mass : | ~50kDa (SDS-PAGE) |
Purity : | ≥95% (SDS-PAGE) |
Stability : | Stable for at least 6 months after receipt when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After reconstitution, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. PBS containing at least 0.1% BSA should be used for further dilutions. |
Concentration : | 0.1mg/ml after reconstitution. |
Gene Name : | FASLG Fas ligand (TNF superfamily, member 6) [ Homo sapiens ] |
Official Symbol : | FASLG |
Synonyms : | FASLG; Fas ligand (TNF superfamily, member 6); APT1LG1, TNFSF6, tumor necrosis factor (ligand) superfamily, member 6; tumor necrosis factor ligand superfamily member 6; CD178; FasL; APTL; CD95 ligand; fas antigen ligand; apoptosis antigen ligand; apoptosis (APO-1) antigen ligand 1; tumor necrosis factor (ligand) superfamily, member 6; FASL; CD95L; CD95-L; TNFSF6; APT1LG1; |
Gene ID : | 356 |
mRNA Refseq : | NM_000639 |
Protein Refseq : | NP_000630 |
MIM : | 134638 |
UniProt ID : | P48023 |
Chromosome Location : | 1q23 |
Pathway : | Activation of Pro-Caspase 8, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Allograft rejection, organism-specific biosystem; Allograft rejection, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; |
Function : | cytokine activity; protein binding; receptor binding; tumor necrosis factor receptor binding; |
Products Types
◆ Recombinant Protein | ||
FASLG-12H | Active Recombinant Human FASLG Protein (139-281, Multimeric), FLAG tagged | +Inquiry |
FASLG-3855H | Recombinant Human FASLG Protein | +Inquiry |
FASLG-3857H | Recombinant Human FASLG Protein, GST-tagged | +Inquiry |
FASLG-1931R | Recombinant Rat FASLG Protein, His (Fc)-Avi-tagged | +Inquiry |
FASLG-259C | Recombinant Cynomolgus Monkey FASLG Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
FASLG-6324HCL | Recombinant Human FASLG 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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