Recombinant Rat Fto, His-tagged
Cat.No. : | Fto-273R |
Product Overview : | Rat FTO (aa 2-502) is fused at the N-terminus to a His-tag. |
- Specification
- Gene Information
- Related Products
Description : | FTO (Fat mass-and obesity-associated gene) is the responsible gene for mouse ‘fused toes’ mutation. An association between FTO genotype and type 2 diabetes has been confirmed. The presence of the FTO rs9939609 A-allele was found to be positively correlated with other symptoms of the metabolic syndrome, including higher fasting insulin, glucose, triglycerides, and lower HDL-cholesterol. |
Source : | E. coli |
Species : | Rat |
Tag : | His |
Form : | Liquid. 0.2μm-filtered solution in 50mM TRIS-Cl, pH 8.2, containing 150mM NaCl, 1mM DTT. |
Molecular Mass : | ~55kDa (SDS-PAGE) |
Purity : | Purified using Ni-NTA column and FPLC. |
Stability : | Working aliquots are stable for up to 3 months when stored at -20°C. |
Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. After opening, prepare aliquots and store at -20°C. Avoid freeze/thaw cycles. For maximum product recovery after thawing, centrifuge the vial before opening the cap. |
Gene Name : | Fto fat mass and obesity associated [ Rattus norvegicus ] |
Official Symbol : | Fto |
Synonyms : | FTO; fat mass and obesity associated; alpha-ketoglutarate-dependent dioxygenase FTO; protein fto; fat mass and obesity-associated protein; RGD1305121; |
Gene ID : | 291905 |
mRNA Refseq : | NM_001039713 |
Protein Refseq : | NP_001034802 |
Function : | DNA-N1-methyladenine dioxygenase activity; DNA-N1-methyladenine dioxygenase activity; ferrous iron binding; ferrous iron binding; metal ion binding; molecular_function; oxidative DNA demethylase activity; oxidative DNA demethylase activity; oxidative RNA demethylase activity; oxidative RNA demethylase activity; oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen; |
Products Types
◆ Recombinant Protein | ||
Fto-3101M | Recombinant Mouse Fto Protein, Myc/DDK-tagged | +Inquiry |
FTO-1054H | Recombinant Human FTO Protein (T32-P505), Tag Free | +Inquiry |
FTO-944H | Recombinant Human FTO Protein, His (Fc)-Avi-tagged | +Inquiry |
FTO-1055H | Recombinant Human FTO Protein (T32-P505), His tagged | +Inquiry |
FTO-14H | Recombinant Human FTO Protein, His-tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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