Recombinant Human IL6, Fc-tagged
| Cat.No. : | IL6-318H |
| Product Overview : | The extracellular domain of human IL-6 (aa 30-212) is fused to the N-terminus of the Fc region of human IgG1. |
- Specification
- Gene Information
- Related Products
| Description : | Interleukin 6 (IL-6) is a pleiotropic alpha-helical cytokine that plays important roles in acute phase reactions, inflammation, hematopoiesis, bone metabolism and cancer progression. IL-6 activity is essential for the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. It is secreted by multiple cell types as a 22kDa-28kDa phosphorylated and variably glycosylated molecule. IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6R) and a signal transducing subunit (gp130). IL-6 is a key factor for the growth of plasma cells. |
| Source : | CHO Cells |
| Species : | Human |
| Tag : | Fc |
| Form : | Lyophilized from 0.2μm-filtered solution in PBS. |
| Purity : | ≥98% (SDS-PAGE) |
| Stability : | Stable for at least 1 year after receipt when stored at -20°C. Working aliquots are stable for up to 3 months when stored at -20°C. |
| Storage : | Short Term Storage: +4°C; Long Term Storage: -20°C. Avoid freeze/thaw cycles. |
| Gene Name : | IL6 interleukin 6 (interferon, beta 2) [ Homo sapiens ] |
| Official Symbol : | IL6 |
| Synonyms : | IL6; interleukin 6 (interferon, beta 2); IFNB2; interleukin-6; BSF2; HGF; HSF; IL 6; CDF; BSF-2; IFN-beta-2; interferon beta-2; interleukin BSF-2; hybridoma growth factor; CTL differentiation factor; B-cell stimulatory factor 2; B-cell differentiation factor; IL-6; |
| Gene ID : | 3569 |
| mRNA Refseq : | NM_000600 |
| Protein Refseq : | NP_000591 |
| MIM : | 147620 |
| UniProt ID : | P05231 |
| Chromosome Location : | 7p21-p15 |
| Pathway : | ATF-2 transcription factor network, organism-specific biosystem; Adipogenesis, organism-specific biosystem; African trypanosomiasis, organism-specific biosystem; African trypanosomiasis, conserved biosystem; Amoebiasis, organism-specific biosystem; Amoebiasis, conserved biosystem; Androgen Receptor Signaling Pathway, organism-specific biosystem; |
| Function : | cytokine activity; cytokine activity; growth factor activity; interleukin-6 receptor binding; contributes_to interleukin-6 receptor binding; interleukin-6 receptor binding; |
Products Types
| ◆ Lysates | ||
| IL6-5224HCL | Recombinant Human IL6 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket
