Native Human Collagen type VI

• Cat.No.: COL6-116H
• Product Overview: Native Human Collagen type VI was purified from Human Placenta.

Specification

• Description: Collagen type VI is a form of collagen primarily associated with the extracellular matrix of skeletal muscle. Collagen type VI is associated with the genes COL6A1, COL6A2, and COL6A3. Defects in collagen VI are associated with Bethlem myopathy and Ullrich congenital muscular dystrophy.
• Source: Human Placenta
• Species: Human
• Form: Liquid (sterile filtered)
• Purity: Human Collagen type VI has been prepared from Human Placenta and is chromatographically and immunologically pure. This product is free from other collagens, human serum proteins and non-collagen extracellular matrix proteins.
• Applications: Human Collagen type VI purified protein standard is used as a control in ELISA and western blot. Collagen type VI is recognized by type specific anti-collagen antibodies that recognize a native three-dimensional structure.ELISA : 1:10,000Western Blot : 1:1000Immunohistochemistry: 1:100-1:500Other Dilution: User Optimized
• Storage: Store vial at 4 ºC prior to opening. This product is stable at 4 ºC as an undiluted liquid. Dilute only prior to immediate use.
• Concentration: 1.0 mg/mL by dry weight
• Storage Buffer: 0.5 M Acetic Acid
• Preservative: 0.01% (w/v) Sodium Azide

Gene Information

• Gene Name: COL6A1 collagen, type VI, alpha 1 [ Homo sapiens (human) ]
• Official Symbol: COL6A1
• Synonyms: collagen, type VI, alpha 1; OPLL; COL6A1; collagen alpha-1(VI) chain; alpha 1 (VI) chain (61 AA); collagen VI, alpha-1 polypeptide; human mRNA for collagen VI alpha-1 C-terminal globular domain9
• Gene ID: 1291
• mRNA Refseq: NM_001848
• Protein Refseq: NP_001839
• MIM: 120220
• UniProt ID: P12109
• Chromosome Location: 21q22.3
• Pathway: Assembly of collagen fibrils and other multimeric structures; Collagen biosynthesis and modifying enzymes; ECM-receptor interaction; NCAM1 interactions
• Function: platelet-derived growth factor binding