Recombinant Mouse CCL20 protein
Cat.No. : | CCL20-50M |
Product Overview : | Recombinant Mouse CCL20 protein was expressed in Escherichia coli. |
- Specification
- Gene Information
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Description : | CCL20, also named LARC (Liver and Activation-regulated Chemokine), is encoded by CCL20 located on chromosome 1 in mouse. The expression can be induced by LPS and some inflammatory cytokines, and it is at a high level in lymph nodes, PBL, fatal liver, fatal lung, appendix and so on. CCL20 has functions of chemotactic towards lymphocytes and dendritic cells. Additionally, it promotes the adhesion of memory CD4+ T cells and inhibits colony formation of bone marrow myeloid immature progenitors. CCL20 elicits it effects by binding with CCR6 receptor. |
Source : | E.coli |
Species : | Mouse |
Form : | Lyophilized from a 0.2μm filtered concentrated solution in PBS, pH 7.4. |
Bio-activity : | Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR6 transfected murine BaF3 cells is in a concentration range of 0.1-10 ng/ml. |
Molecular Mass : | Approximately 8.0 kDa, a single non-glycosylated polypeptide chain containing 70 amino acids. |
Protein length : | 70 |
AA Sequence : | ASNYDCCLSYIQTPLPSRAIVGFTR QMADEACDINAIIFHTKKRKSVCAD PKQNWVKRAVNLLSLRVKKM |
Endotoxin : | Less than 1 EU/µg of rMuMIP-3α/CCL20 as determined by LAL method. |
Purity : | >96% by SDS-PAGE and HPLC analysis. |
Storage : | Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 centigrade as supplied. 1 month, 2 to 8 centigrade under sterile conditions after reconstitution. 3 months, -20 to -70 centigrade under sterile conditions after reconstitution. |
Reconstitution : | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤-20 centigrade. Further dilutions should be made in appropriate buffered solutions. |
Gene Name : | CCL20 |
Official Symbol : | CCL20 |
Synonyms : | CCL20; chemokine (C-C motif) ligand 20; C-C motif chemokine 20; MIP-3-alpha; CC chemokine LARC; CC chemokine ST38; beta chemokine exodus-1; beta-chemokine exodus-1; small-inducible cytokine A20; small inducible cytokine subfamily A20; macrophage inflammatory protein 3 alpha; liver and activation-regulated chemokine; CKb4; LARC; ST38; MIP3A; MIP-3A; Scya20; MIP-3[a]; exodus-1; |
Gene ID : | 20297 |
mRNA Refseq : | NM_001159738 |
Protein Refseq : | NP_001153210 |
UniProt ID : | O89093 |
Products Types
◆ Recombinant Protein | ||
CCL20-517H | Active Recombinant Human CCL20 Protein, HIgG1 Fc-tagged | +Inquiry |
CCL20-22H | Active Recombinant Human CCL20 Protein | +Inquiry |
CCL20-073C | Active Recombinant Human CCL20 Protein (70 aa) | +Inquiry |
CCL20-3403M | Recombinant Mouse CCL20 protein(Ala28-Met97) | +Inquiry |
CCL20-18M | Recombinant Mouse CCL20 Protein | +Inquiry |
◆ Lysates | ||
CCL20-447MCL | Recombinant Mouse CCL20 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (7)
Ask a questionCCL20 influences dendritic cell migration and differentiation, crucial for initiating immune responses.
CCL20 contributes to cancer progression by shaping the tumor microenvironment and aiding tumor cell invasion.
CCL20 plays a significant role in autoimmune diseases by attracting inflammatory cells to affected joints.
CCL20 is involved in wound healing and tissue repair, facilitating immune cell migration and tissue regeneration.
Changes in CCL20 expression impact skin health, potentially contributing to the development of skin disorders.
CCL20 recruits and activates immune cells to sites of inflammation, coordinating the immune response.
CCL20 impacts mucosal immunity, playing a critical role in immune defense in the gut and respiratory system.
Customer Reviews (3)
Write a reviewExpert protein engineering support, essential for our projects' progress.
Consistent western blot results, an indispensable tool in our lab.
Dependable protein quantification, ensures data precision in our work.
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