Recombinant Human CFP, His-tagged
Cat.No. : | CFP-252H |
Product Overview : | CFP, 28-469aa, Human, His tag, E.coli |
- Specification
- Gene Information
- Related Products
Description : | CFP is a plasma glycoprotein that positively regulates the alternative complement pathway of the innate immune system. This protein binds to many microbial surfaces and apoptotic cells and stabilizes the C3- and C5-convertase enzyme complexes in a feedback loop that ultimately leads to formation of the membrane attack complex and lysis of the target cell. Mutations in this gene result in two forms of properdin deficiency, which results in high susceptibility to meningococcal infections. Multiple alternatively spliced variants, encoding the same protein, have been identified. Recombinant human CFP protein, fused to His-tag at N-terminus, was expressed in E.coli. |
Source : | E.coli |
Species : | Human |
Tag : | His-tag |
Form : | Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.4M Urea, 10% glycerol |
Molecular Mass : | 50.9 kDa (465aa) |
Protein length : | 28-469aa |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSDPVLCFT QYEESSGKCK GLLGGGVSVE DCCLNTAFAY QKRSGGLCQP CRSPRWSLWS TWAPCSVTCS EGSQLRYRRC VGWNGQCSGK VAPGTLEWQL QACEDQQCCP EMGGWSGWGP WEPCSVTCSK GTRTRRRACN HPAPKCGGHC PGQAQESEAC DTQQVCPTHG AWATWGPWTP CSASCHGGPH EPKETRSRKC SAPEPSQKPP GKPCPGLAYE QRRCTGLPPC PVAGGWGPWG PVSPCPVTCG LGQTMEQRTC NHPVPQHGGP FCAGDATRTH ICNTAVPCPV DGEWDSWGEW SPCIRRNMKS ISCQEIPGQQ SRGRTCRGRK FDGHRCAGQQ QDIRHCYSIQ HCPLKGSWSE WSTWGLCMPP CGPNPTRARQ RLCTPLLPKY PPTVSMVEGQ GEKNVTFWGR PLPRCEELQG QKLVVEEKRP CLHVPACKDP EEEEL |
Purity : | >80% by SDS - PAGE |
Storage : | Can be stored at +4C short term (1-2 weeks). For long term storage, aliquot and store at -20C or -70C. Avoid repeated freezing and thawing cycles. |
Concentration : | 1 mg/ml (determined by Bradford assay) |
Gene Name : | CFP complement factor properdin [ Homo sapiens ] |
Official Symbol : | CFP |
Synonyms : | CFP; complement factor properdin; PFC, properdin P factor, complement; properdin; complement factor P; properdin P factor, complement; BFD; PFC; PFD; PROPERDIN; |
Gene ID : | 5199 |
mRNA Refseq : | NM_001145252 |
Protein Refseq : | NP_001138724 |
MIM : | 300383 |
UniProt ID : | P27918 |
Chromosome Location : | Xp11.4 |
Pathway : | Herpes simplex infection, organism-specific biosystem; Herpes simplex infection, conserved biosystem; |
Products Types
◆ Recombinant Protein | ||
CFP-2152M | Recombinant Mouse CFP Protein (23-464 aa), His-tagged | +Inquiry |
CFP-002E | Recombinant Cyan Fluorescent Protein, His-tagged | +Inquiry |
Cfp-769M | Recombinant Mouse Cfp Protein, His-tagged | +Inquiry |
CFP-1179H | Recombinant Human CFP Protein, GST-Tagged | +Inquiry |
Cfp-770R | Recombinant Rat Cfp Protein, His-tagged | +Inquiry |
◆ Native Protein | ||
CFP-106H | Active Native Human Complement Factor P (Properdin) | +Inquiry |
◆ Lysates | ||
CFP-7552HCL | Recombinant Human CFP 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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