Recombinant Human CD19, Fc-tagged, Biotinylated
| Cat.No. : | CD19-280H |
| Product Overview : | Biotinylated Human CD19 Protein, With C-Fc Tag (Biotinylated rhCD19-Fc) Pro 20 - Lys 291, was labeled with biotin based on rhCD19-Fc Protein, which was produced in human 293 cells (HEK293). |
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| Description : | Lymphocytes proliferate and differentiate in response to various concentrations of different antigens. The ability of the B cell to respond in a specific, yet sensitive manner to the various antigens is achieved with the use of low-affinity antigen receptors. This gene encodes a cell surface molecule which assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. |
| Source : | HEK293 |
| Species : | Human |
| Tag : | Fc |
| Form : | Lyophilized from 0.22 μm filtered solution in PBS, pH7.4. Normally Trehalose are added as protectants before lyophilization. |
| Molecular Mass : | Biotinylated rhCD19-Fc, fused with Fc fragment of human IgG1 at the C-terminus, has a calculated MW of 56.3 kDa. The predicted N-terminus is Pro 20. DTT-reduced Protein migrates as 56-66 kDa due to glycosylation. |
| Endotoxin : | Less than 1.0 EU per μg of the Biotinylated rhCD19-Fc by the LAL method. |
| Purity : | >95% as determined by reduced SDS-PAGE. |
| Storage : | Avoid repeated freeze-thaw cycles. No activity loss was observed after storage at: In lyophilized state for 1 year (4°C); After reconstitution under sterile conditions for 3 months (-70°C). |
| Gene Name : | CD19 CD19 molecule [ Homo sapiens ] |
| Official Symbol : | CD19 |
| Synonyms : | CD19; CD19 molecule; CD19 antigen; B-lymphocyte antigen CD19; differentiation antigen CD19; T-cell surface antigen Leu-12; B-lymphocyte surface antigen B4; B4; CVID3; MGC12802; |
| Gene ID : | 930 |
| mRNA Refseq : | NM_001178098 |
| Protein Refseq : | NP_001171569 |
| MIM : | 107265 |
| UniProt ID : | P15391 |
| Chromosome Location : | 16p11.2 |
| Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen Activates B Cell Receptor Leading to Generation of Second Messengers, organism-specific biosystem; B Cell Receptor Signaling Pathway, organism-specific biosystem; B cell receptor signaling pathway, organism-specific biosystem; B cell receptor signaling pathway, conserved biosystem; BCR signaling pathway, organism-specific biosystem; Hematopoietic cell lineage, organism-specific biosystem; |
| Function : | receptor signaling protein activity; |
Products Types
| ◆ Lysates | ||
| CD19-2005HCL | Recombinant Human CD19 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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