Recombinant Human NCSTN, His-tagged

• Cat.No.: NCSTN-1217H
• Product Overview: Recombinant Human NCSTN protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.

Specification

• Source: E.coli
• Species: Human
• Tag: His
• Protein length: 338-689aa
• Storage: The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
• Storage Buffer: 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.

Gene Information

• Gene Name: NCSTN nicastrin [ Homo sapiens ]
• Official Symbol: NCSTN
• Synonyms: NCSTN; nicastrin; APH2; KIAA0253; ATAG1874; anterior pharynx-defective 2; RP11-517F10.1
• Gene ID: 23385
• mRNA Refseq: NM_015331
• Protein Refseq: NP_056146
• MIM: 605254
• UniProt ID: Q92542
• Chromosome Location: 1q22-q23
• Pathway: Activated NOTCH1 Transmits Signal to the Nucleus, organism-specific biosystem; Alzheimers disease, organism-specific biosystem; Alzheimers disease, conserved biosystem; Cell death signalling via NRAGE, NRIF and NADE, organism-specific biosystem; Delta-Notch Signaling Pathway, organism-specific biosystem; NRIF signals cell death from the nucleus, organism-specific biosystem; Notch signaling pathway, organism-specific biosystem
• Function: aspartic-type endopeptidase activity; endopeptidase activity; peptidase activity; protein binding