Recombinant Human NQO1, GST-tagged
Cat.No. : | NQO1-1352H |
Product Overview : | Recombinant Human NQO1 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
Unit | |
Price | |
Qty |
- Specification
- Gene Information
- Related Products
Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-274aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Publication : |
NQO1 regulates mitotic progression and response to mitotic stress through modulating SIRT2 activity (2018)
|
Gene Name : | NQO1 NAD(P)H dehydrogenase, quinone 1 [ Homo sapiens ] |
Official Symbol : | NQO1 |
Synonyms : | NQO1; NAD(P)H dehydrogenase, quinone 1; DIA4, diaphorase (NADH/NADPH) (cytochrome b 5 reductase) , NMOR1; NAD(P)H dehydrogenase [quinone] 1; DHQU; DTD; QR1; azoreductase; diaphorase-4; DT-diaphorase; dioxin-inducible 1; menadione reductase; quinone reductase 1; phylloquinone reductase; NAD(P)H:quinone oxireductase; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); DIA4; NMOR1; NMORI; |
Gene ID : | 1728 |
mRNA Refseq : | NM_000903 |
Protein Refseq : | NP_000894 |
UniProt ID : | P15559 |
Chromosome Location : | 16q12-q22 |
Pathway : | Keap1-Nrf2 Pathway, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Oxidative Stress, organism-specific biosystem; Regulation of ornithine decarboxylase (ODC), organism-specific biosystem; |
Function : | NAD(P)H dehydrogenase (quinone) activity; coenzyme binding; cytochrome-b5 reductase activity; electron carrier activity; oxidoreductase activity; protein binding; |
Products Types
◆ Recombinant Protein | ||
Nqo1-4482M | Recombinant Mouse Nqo1 Protein, Myc/DDK-tagged | +Inquiry |
NQO1-3717R | Recombinant Rat NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-6062H | Recombinant Human NQO1 Protein, GST-tagged | +Inquiry |
NQO1-1534H | Recombinant Human NQO1 Protein, His (Fc)-Avi-tagged | +Inquiry |
NQO1-001H | Active Recombinant Human NQO1 Protein | +Inquiry |
◆ Lysates | ||
NQO1-3725HCL | Recombinant Human NQO1 293 Cell Lysate | +Inquiry |
◆ Assay kits | ||
Kit-0633 | NQO1 Activity Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
- Q&As
- Reviews
Q&As (6)
Ask a questionMutations in NQO1 can be detected and analyzed by methods such as whole-genome sequencing or target region sequencing to understand the impact of mutations on protein structure and function.
The types of mutations in NQO1 include point mutations, insertions/deletions, duplications, etc., which can cause structural and functional abnormalities of the protein.
Abnormal NQO1 levels may indicate cancer, neurodegenerative diseases, and oxidative stress-related diseases.
Studying the regulatory mechanism of NQO1 requires a combination of various experimental methods and techniques, such as gene knockout, transcriptome analysis, and protein-protein interactions.
This protein can be used as a biomarker in medical treatment to help monitor disease progression and treatment efficacy. In addition, therapeutics targeting NQO1, such as gene therapy or modulating its expression, are also being studied.
NQO1 has a complex relationship with other genes or proteins, and can interact with other genes or proteins and participate in a variety of biochemical reactions.
Ask a Question for All NQO1 Products
Required fields are marked with *
My Review for All NQO1 Products
Required fields are marked with *
Inquiry Basket