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Recombinant Human SORD, His-tagged

Cat.No. : SORD-2878H
Product Overview : Recombinant Human SORD protein, fused to His-tag, was expressed in E.coli and purified by Ni-sepharose.
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Source : E.coli
Species : Human
Tag : His
Protein length : 1-357aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 300mM Imidazole and 0.7% Sarcosyl, 15%glycerol.
Gene Name : SORD sorbitol dehydrogenase [ Homo sapiens ]
Official Symbol : SORD
Synonyms : SORD; sorbitol dehydrogenase; L-iditol 2-dehydrogenase; SORD1;
Gene ID : 6652
mRNA Refseq : NM_003104
Protein Refseq : NP_003095
MIM : 182500
UniProt ID : Q00796
Chromosome Location : 15q15-q21.1
Pathway : Fructose and mannose metabolism, organism-specific biosystem; Fructose and mannose metabolism, conserved biosystem; Metabolic pathways, organism-specific biosystem; sorbitol degradation I, organism-specific biosystem;
Function : L-iditol 2-dehydrogenase activity; L-iditol 2-dehydrogenase activity; NAD binding; metal ion binding; oxidoreductase activity; sugar binding; zinc ion binding; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What diseases are SORD proteins associated with? 09/22/2022

At present, the association between SORD protein and disease is not well understood, and further research is needed to explore its role in specific diseases.

How are SORD proteins related to antioxidants? 06/22/2022

SORD protein is involved in the antioxidant process in cells, and may indirectly affect the antioxidant capacity in cells by regulating heptitol-6-phosphate metabolism.

Are SORD protein mutations associated with genetic disorders? 06/14/2022

There is no clear information on the association between SORD protein mutations and inherited diseases.

Does the loss of function of the SORD protein lead to disease? 09/04/2021

There is no evidence that the lack of SORD protein function directly leads to the development of disease. However, it may affect the normal function of the glucose metabolism pathway.

How is SORD protein related to metabolic diseases? 12/07/2020

The protein may play a role in metabolic pathways related to metabolic diseases (e.g., diabetes mellitus and metabolic syndrome), but the specific relationship still needs to be further studied.

What is the function of SORD protein in the human body? 03/03/2020

SORD protein is involved in the heptylol-6-phosphoreductase reaction in the glucose metabolism pathway, which converts heptitol-6-phosphate to cholesterol alcohol.

Customer Reviews (3)

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Reviews
01/12/2023

    The stability of SORD products allows them to cope with different experimental conditions and modes of operation.

    12/03/2021

      SORD has a high specific activity and can exert strong biological effects at low concentrations.

      07/05/2021

        When experiments were performed with SORD, the reproducibility of the results was excellent.

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