Recombinant Human TFEB, GST-tagged
Cat.No. : | TFEB-3202H |
Product Overview : | Recombinant Human TFEB protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 1-476aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | TFEB transcription factor EB [ Homo sapiens ] |
Official Symbol : | TFEB |
Synonyms : | TFEB; transcription factor EB; bHLHe35; TCFEB; T-cell transcription factor EB; class E basic helix-loop-helix protein 35; BHLHE35; ALPHATFEB; |
Gene ID : | 7942 |
mRNA Refseq : | NM_001167827 |
Protein Refseq : | NP_001161299 |
MIM : | 600744 |
UniProt ID : | P19484 |
Chromosome Location : | 6p21 |
Function : | DNA binding; protein heterodimerization activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; sequence-specific DNA binding transcription factor activity; transcription regulato |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (5)
Ask a questionYes, TFEB activation can enhance the autophagic process by upregulating the expression of autophagy-related genes and promoting the formation of autophagosomes.
TFEB activation has been shown to enhance the clearance of protein aggregates commonly associated with neurodegenerative disorders, offering potential therapeutic benefits.
Several small molecule compounds have been identified as potential TFEB activators, and their therapeutic potential is being explored in preclinical studies.
TFEB regulates the expression of genes involved in lysosomal biogenesis, promoting the formation and function of lysosomes.
Yes, TFEB has been shown to regulate the expression of genes involved in inflammation, suggesting its potential role in modulating the immune response.
Customer Reviews (3)
Write a reviewOne notable advantage of the TFEB protein is the outstanding technical support provided by the manufacturer.
One aspect that sets the TFEB protein apart is the excellent technical support provided by the manufacturer.
The TFEB protein has demonstrated remarkable stability, allowing for extended storage without compromising its quality.
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