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Recombinant Human UBA2, GST-tagged

Cat.No. : UBA2-3515H
Product Overview : Recombinant Human UBA2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose.
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Source : E.coli
Species : Human
Tag : GST
Protein length : 294-640aa
Storage : The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles.
Storage Buffer : 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol.
Gene Name : UBA2 ubiquitin-like modifier activating enzyme 2 [ Homo sapiens ]
Official Symbol : UBA2
Synonyms : UBA2; ubiquitin-like modifier activating enzyme 2; SAE2, SUMO1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; ARX; FLJ13058; HRIHFB2115; ubiquitin activating enzyme E1 homolog (yeast); SUMO1 activating enzyme subunit 2; SUMO-1 activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; anthracycline-associated resistance ARX; UBA2, ubiquitin-activating enzyme E1 homolog; SAE2;
Gene ID : 10054
mRNA Refseq : NM_005499
Protein Refseq : NP_005490
MIM : 613295
UniProt ID : Q9UBT2
Chromosome Location : 19q13.11
Pathway : Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organi
Function : ATP binding; SUMO activating enzyme activity; enzyme activator activity; ligase activity; metal ion binding; nucleotide binding; protein binding; protein heterodimerization activity; transcription factor binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (6)

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What is the correlation between the expression level of UBA2 and disease? 10/01/2023

Studies have shown that UBA2 expression levels are associated with the occurrence and development of certain diseases, including cancer and neurodegenerative diseases.

What are the specific roles of UBA2 in cancer? 06/07/2023

In cancer, UBA2 may contribute to tumorigenesis and development by regulating intracellular protein degradation and signal transduction. It could be a potential target for cancer treatment.

How to detect UBA2 expression level? 01/22/2023

The expression level of UBA2 can be detected by immunohistochemistry, western blot and real-time quantitative PCR.

How about the interactions of UBA2 with other proteins? 12/19/2022

UBA2 can interact with a variety of other proteins, including ubiquitin ligase, proteolytic enzyme, etc. These interactions enable it to regulate processes such as cell growth, differentiation, and apoptosis.

Does there have relationship between the structure and function of UBA2? 01/15/2022

The structure of UBA2 determines its ability and stability to bind to other proteins. The study of its structure can help us understand its function and mechanism of action.

What are the therapeutic strategies for UBA2? 10/20/2021

Therapeutic strategies for UBA2 may include regulating its expression level, inhibiting its enzyme activity, or regulating its associated signal transduction pathways. These methods may have potential applications in the treatment of cancer, neurodegenerative diseases, etc.

Customer Reviews (3)

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Reviews
05/31/2023

    After UBA2 was used, the background of the Western blot was very clean and there was no non-specific signal.

    10/12/2022

      The recombinant protein in the pathogenesis of related diseases was evaluated by animal models or in vitro experiments, and the effect was found to be good.

      07/04/2021

        This protein has good stability and consistency during large-scale production.

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