Recombinant Human UBA2, GST-tagged
Cat.No. : | UBA2-3515H |
Product Overview : | Recombinant Human UBA2 protein, fused to GST-tag, was expressed in E.coli and purified by GSH-sepharose. |
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- Gene Information
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Source : | E.coli |
Species : | Human |
Tag : | GST |
Protein length : | 294-640aa |
Storage : | The protein is stored in PBS buffer at -20℃. Avoid repeated freezing and thawing cycles. |
Storage Buffer : | 1M PBS (58mM Na2HPO4,17mM NaH2PO4, 68mM NaCl, pH8. ) added with 100mM GSH and 1% Triton X-100,15%glycerol. |
Gene Name : | UBA2 ubiquitin-like modifier activating enzyme 2 [ Homo sapiens ] |
Official Symbol : | UBA2 |
Synonyms : | UBA2; ubiquitin-like modifier activating enzyme 2; SAE2, SUMO1 activating enzyme subunit 2; SUMO-activating enzyme subunit 2; ARX; FLJ13058; HRIHFB2115; ubiquitin activating enzyme E1 homolog (yeast); SUMO1 activating enzyme subunit 2; SUMO-1 activating enzyme subunit 2; ubiquitin-like 1-activating enzyme E1B; anthracycline-associated resistance ARX; UBA2, ubiquitin-activating enzyme E1 homolog; SAE2; |
Gene ID : | 10054 |
mRNA Refseq : | NM_005499 |
Protein Refseq : | NP_005490 |
MIM : | 613295 |
UniProt ID : | Q9UBT2 |
Chromosome Location : | 19q13.11 |
Pathway : | Adaptive Immune System, organism-specific biosystem; Antigen processing: Ubiquitination and Proteasome degradation, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organi |
Function : | ATP binding; SUMO activating enzyme activity; enzyme activator activity; ligase activity; metal ion binding; nucleotide binding; protein binding; protein heterodimerization activity; transcription factor binding; |
Products Types
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UBA2-520H | Recombinant Human UBA2 Protein, His-tagged | +Inquiry |
UBA2-2290H | Recombinant Human UBA2 Protein, His (Fc)-Avi-tagged | +Inquiry |
Uba2-6765M | Recombinant Mouse Uba2 Protein, Myc/DDK-tagged | +Inquiry |
UBA2-4935H | Recombinant Human UBA2 protein, His-SUMO-tagged | +Inquiry |
◆ Lysates | ||
UBA2-606HCL | Recombinant Human UBA2 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionStudies have shown that UBA2 expression levels are associated with the occurrence and development of certain diseases, including cancer and neurodegenerative diseases.
In cancer, UBA2 may contribute to tumorigenesis and development by regulating intracellular protein degradation and signal transduction. It could be a potential target for cancer treatment.
The expression level of UBA2 can be detected by immunohistochemistry, western blot and real-time quantitative PCR.
UBA2 can interact with a variety of other proteins, including ubiquitin ligase, proteolytic enzyme, etc. These interactions enable it to regulate processes such as cell growth, differentiation, and apoptosis.
The structure of UBA2 determines its ability and stability to bind to other proteins. The study of its structure can help us understand its function and mechanism of action.
Therapeutic strategies for UBA2 may include regulating its expression level, inhibiting its enzyme activity, or regulating its associated signal transduction pathways. These methods may have potential applications in the treatment of cancer, neurodegenerative diseases, etc.
Customer Reviews (3)
Write a reviewAfter UBA2 was used, the background of the Western blot was very clean and there was no non-specific signal.
The recombinant protein in the pathogenesis of related diseases was evaluated by animal models or in vitro experiments, and the effect was found to be good.
This protein has good stability and consistency during large-scale production.
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