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Recombinant Human PGR, StrepII-tagged

Cat.No. : PGR-228H
Product Overview : Purified human recombinant progesterone receptor or PR protein (amino acids 412-526, 115 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 11.1 kDa. (Accession NP_000917.3; UniProt P06401) Entrez Gene ID 5241
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  • Gene Information
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Description : This product is a fragment of progesterone receptor. PR, a member of the steroid receptor superfamily, mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 412-526, 115 a.a.
AA Sequence : AAFPDFPLGPPPPLPPRATPSRPGE AAVTAAPASASVSSASSSGSTLECI LYKAEGAPPQQGPFAPPPCKAPGAS GCLLPRDGLPSTSASAAAAGAAPAL YPALGLNGLPQLGYQ
Endotoxin : <0.1 eu per ug protein by lal
Purity : >95% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : PGR progesterone receptor [ Homo sapiens ]
Official Symbol : PGR
Synonyms : PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3;
Gene ID : 5241
mRNA Refseq : NM_000926
Protein Refseq : NP_000917
MIM : 607311
UniProt ID : P06401
Chromosome Location : 11q22-q23
Pathway : Cellular roles of Anthrax toxin, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem;
Function : DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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