Recombinant Human PGR, StrepII-tagged
Cat.No. : | PGR-228H |
Product Overview : | Purified human recombinant progesterone receptor or PR protein (amino acids 412-526, 115 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 11.1 kDa. (Accession NP_000917.3; UniProt P06401) Entrez Gene ID 5241 |
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Description : | This product is a fragment of progesterone receptor. PR, a member of the steroid receptor superfamily, mediates the physiological effects of progesterone, which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
Protein length : | 412-526, 115 a.a. |
AA Sequence : | AAFPDFPLGPPPPLPPRATPSRPGE AAVTAAPASASVSSASSSGSTLECI LYKAEGAPPQQGPFAPPPCKAPGAS GCLLPRDGLPSTSASAAAAGAAPAL YPALGLNGLPQLGYQ |
Endotoxin : | <0.1 eu per ug protein by lal |
Purity : | >95% pure by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
Gene Name : | PGR progesterone receptor [ Homo sapiens ] |
Official Symbol : | PGR |
Synonyms : | PGR; progesterone receptor; NR3C3; PR; nuclear receptor subfamily 3 group C member 3; |
Gene ID : | 5241 |
mRNA Refseq : | NM_000926 |
Protein Refseq : | NP_000917 |
MIM : | 607311 |
UniProt ID : | P06401 |
Chromosome Location : | 11q22-q23 |
Pathway : | Cellular roles of Anthrax toxin, organism-specific biosystem; Gene Expression, organism-specific biosystem; Generic Transcription Pathway, organism-specific biosystem; Nuclear Receptor transcription pathway, organism-specific biosystem; Nuclear Receptors, organism-specific biosystem; Nuclear signaling by ERBB4, organism-specific biosystem; Oocyte meiosis, organism-specific biosystem; |
Function : | DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; receptor activity; receptor binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; zinc ion binding; |
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Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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