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Recombinant Human FCER2, StrepII-tagged

Cat.No. : FCER2-238H
Product Overview : Purified human recombinant CD23 or Low affinity immunoglobulin epsilon Fc protein (amino acids 48-321, 274 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 31 kDa. (Accession NP_001993.2; UniProt P06734)
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  • Gene Information
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Description : CD23 is a B-cell specific antigen, and a low-affinity receptor for IgE. It has essential roles in B cell growth and differentiation, and the regulation of IgE production. This protein is a single-pass type II membrane protein, but also exists as a soluble secreted form, then functioning as a potent mitogenic growth factor.
Source : Human Cells
Species : Human
Tag : StrepII
Form : Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free).
Protein length : 48-321, 274 a.a.
AA Sequence : DTTQSLKQLEERAARNVSQVSKNLE SHHGDQMAQKSQSTQISQELEELRA EQQRLKSQDLELSWNLNGLQADLSS FKSQELNERNEASDL LERLREEVTKLRMELQVSSGFVCNT CPEKWINFQRKCYYFGKGTKQWVHA RYACDDMEGQLVSIHSPEEQDFLTK HASHTGSWIGLRNLDLKGEFIWVD GSHVDYSNWAPGEPTSRSQGEDCVM MRGSGRWNDAFCDRKLGAWVCDRLA TCTPPASEGSAESMGPDSRPDPDGR LPTPSAPLHS
Endotoxin : <0.1 eu per ug protein by lal
Purity : ~90% pure by SDS-PAGE
Storage : 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles.
Reconstitution : Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml.
Gene Name : FCER2 Fc fragment of IgE, low affinity II, receptor for (CD23) [ Homo sapiens ]
Official Symbol : FCER2
Synonyms : FCER2; Fc fragment of IgE, low affinity II, receptor for (CD23); CD23A, Fc fragment of IgE, low affinity II, receptor for (CD23A) , FCE2; low affinity immunoglobulin epsilon Fc receptor; CD23; CLEC4J; BLAST-2; CD23 antigen; fc-epsilon-RII; lymphocyte IgE receptor; immunoglobulin E-binding factor; C-type lectin domain family 4, member J; FCE2; CD23A; IGEBF;
Gene ID : 2208
mRNA Refseq : NM_001207019
Protein Refseq : NP_001193948
MIM : 151445
UniProt ID : P06734
Chromosome Location : 19p13.3
Pathway : Hematopoietic cell lineage, organism-specific biosystem; Hematopoietic cell lineage, conserved biosystem; IL-3 Signaling Pathway, organism-specific biosystem; IL4-mediated signaling events, organism-specific biosystem;
Function : IgE binding; binding; integrin binding; metal ion binding; receptor activity; sugar binding;

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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