Recombinant Human WNT3A, StrepII-tagged
Cat.No. : | WNT3A-265H |
Product Overview : | Purified, full-length human recombinant WNT3A protein (amino acids 19-352, 334 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 37.4 kDa. (Accession NP_149122.1; UniProt P56704) |
- Specification
- Gene Information
- Related Products
Description : | WNT3A is a member of the WNT gene family. It plays distinct roles in cell-cell signaling during morphogenesis of the developing neural tube. Palmitoylation at Ser-209 is required for efficient binding to frizzled receptors. It is also required for subsequent palmitoylation at Cys-77. Palmitoylation is necessary for proper trafficking to cell surface. |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free). |
Protein length : | 19-352, 334 a.a. |
AA Sequence : | SYPIWWSLAVGPQYSSLGSQPILCA SIPGLVPKQLRFCRNYVEIMPSVAE GIKIGIQECQHQFRGRRWNCTTVHD SLAIFGPVLDKATRESAFVHAIASA GVAFAVTRSCAEGTAAICGCSSRHQ GSPGKGWKWGGCSEDIEFGGMVSRE FADARENRPDARSAMNRHNNEAGRQ AIASHMHLKCKCHGLSGSCEVKTCW WSQPDFRAIGDFLKDKYDSASEMVV EKHRESRGWVETLRPRYTYFKVPTE RDLVYYEASPNFCEPNPETGSFGTR DRTCNVSSHGIDGCDLLCCGRGHNA RAERRREKCRCVFHWCCYVSCQECT RVYDVHTCK |
Endotoxin : | <0.1 eu per ug protein by lal |
Purity : | >80% by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml. |
Gene Name : | WNT3A wingless-type MMTV integration site family, member 3A [ Homo sapiens ] |
Official Symbol : | WNT3A |
Synonyms : | WNT3A; wingless-type MMTV integration site family, member 3A; protein Wnt-3a; MGC119418; MGC119419; MGC119420; |
Gene ID : | 89780 |
mRNA Refseq : | NM_033131 |
Protein Refseq : | NP_149122 |
MIM : | 606359 |
UniProt ID : | P56704 |
Chromosome Location : | 1q42 |
Pathway : | Basal cell carcinoma, organism-specific biosystem; Basal cell carcinoma, conserved biosystem; Canonical Wnt signaling pathway, organism-specific biosystem; Class B/2 (Secretin family receptors), organism-specific biosystem; DNA damage response (only ATM dependent), organism-specific biosystem; GPCR ligand binding, organism-specific biosystem; HTLV-I infection, organism-specific biosystem; |
Function : | extracellular matrix structural constituent; frizzled-2 binding; protein binding; protein domain specific binding; receptor agonist activity; transcription coactivator activity; |
Products Types
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◆ Lysates | ||
WNT3A-295HCL | Recombinant Human WNT3A 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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