Recombinant Human IFNL2, StrepII-tagged
Cat.No. : | IFNL2-298H |
Product Overview : | Purified, full-length human recombinant IFNL2 (IL28A) protein (amino acids 26-200, 175 a.a.) with StrepII tag, produced in human cells. Predicted molecular weight: 19.8 kDa. (Accession NP_742150.1; UniProt Q8IZJ0) |
- Specification
- Gene Information
- Related Products
Description : | This is a cytokine distantly related to type I interferons and the IL-10 family. This protein, interleukin 29 (IL29), and interleukin 28B (IL28B) are three closely related cytokine genes that form a cytokine gene cluster on a chromosomal region mapped to 19q13. Expression of the cytokines encoded by the three genes can be induced by viral infection. All three cytokines have been shown to interact with a heterodimeric class II cytokine receptor that consists of interleukin 10 receptor, beta (IL10RB) and interleukin 28 receptor, alpha (IL28RA). |
Source : | Human Cells |
Species : | Human |
Tag : | StrepII |
Form : | Lyophilized from sterile 0.2μm filtered solution in 0.3X PBS with 10% Trehalose (carrier-free) |
Protein length : | 26-200, 175 a.a. |
AA Sequence : | VPVARLHGALPDARGCHIAQFKSLS PQELQAFKRAKDALEESLLLKDCRC HSRLFPRTWDLRQLQVRERPMALEA ELALTLKVLEATADTDPALVDVLDQ PLHTLHHILSQFRACIQPQPTAGPR TRGRLHHWLYRLQEAPKKESPGCLE ASVTFNLFRLLTRDLNCVASGDLCV |
Endotoxin : | <0.1 eu per μg protein by lal |
Purity : | ~85% by SDS-PAGE |
Storage : | 12 months at -20°C as supplied; 1 month at 4°C after reconstitution. Avoid freeze/thaw cycles. |
Reconstitution : | Centrifuge the vial prior to opening. Reconstitute in PBS to a concentration of 0.1 mg/ml |
Gene Name : | IL28A interleukin 28A (interferon, lambda 2) [ Homo sapiens ] |
Official Symbol : | IFNL2 |
Synonyms : | IL28A; interleukin 28A (interferon, lambda 2); interleukin 28A; interleukin-28A; IFNL2; IL 28A; IFN-lambda-2; cytokine Zcyto20; interferon lambda 2; interferon lambda-2; interferon-lambda 2; IL-28A; |
Gene ID : | 282616 |
mRNA Refseq : | NM_172138 |
Protein Refseq : | NP_742150 |
MIM : | 607401 |
UniProt ID : | Q8IZJ0 |
Chromosome Location : | 19q13.13 |
Pathway : | Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Jak-STAT signaling pathway, organism-specific biosystem; Jak-STAT signaling pathway, conserved biosystem; |
Function : | cytokine activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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